Targeting neuropilin-1 to inhibit prostate cancer invasion and metastasis
| Data(s) |
2015
|
|---|---|
| Resumo |
Recent reports provide evidence that the epithelial-to-mesenchymal transition (EMT) plays a key role in prostate cancer (PCa) metastasis and therapy resistance. We have recently identified the cell surface receptor, Neuropilin-1 (NRP1) to be increased during epithelial-mesenchymal transition (EMT) and this study aims to determine whether the inhibition of NRP1 will be a feasible therapeutic strategy for blocking PCa metastasis and therapy resistance. |
| Formato |
application/pdf |
| Identificador | |
| Publicador |
Wiley-Blackwell |
| Relação |
http://eprints.qut.edu.au/94827/8/94827.pdf http://onlinelibrary.wiley.com/doi/10.1111/bju.2015.116.issue-S1/issuetoc Volpert, Marianna, Tse, Brian W.C., Stylianou, Nataly, Ratther, Ellca, McPherson, Stephen, Costa, Taylor, McGowan, Kayla, Lehman, Melanie, Fazli, Ladan, Gleave, Martin, Russell, Pamela, Gunter, Jennifer H., Williams, Elizabeth D., Nelson, Colleen, & Hollier, Brett G. (2015) Targeting neuropilin-1 to inhibit prostate cancer invasion and metastasis. In 2nd Prostate Cancer World Congress, 17-21 August 2015, Cairns Convention Centre, Cairns, Qld. |
| Direitos |
Copyright 2015 The Author(s) |
| Fonte |
School of Biomedical Sciences; Faculty of Health; Institute of Health and Biomedical Innovation |
| Palavras-Chave | #111201 Cancer Cell Biology #111207 Molecular Targets #neuropilin-1 #prostate cancer #cancer invasion #metastasis |
| Tipo |
Conference Item |
