Asymmetric total synthesis of erythromycin. 3. Total synthesis of erythromycin
| Data(s) |
1981
|
|---|---|
| Resumo |
In the preceding paper' we described the preparation of the key lactone intermediate la in optically active form. In this paper we report the synthesis of erythromycin (2) from la. In essence,this transformation involves the glycosidation of a suitable derivative of la with L-cladinose and D-desosamine and the generation of the C-9 ketone functionality. |
| Formato |
application/pdf |
| Identificador |
http://eprints.iisc.ernet.in/25681/1/62.pdf Woodward, RB and Logusch, E and Nambiar, KP and Sakan, K and Ward, DE and Au-Yeung, BW and Balaram, Padmanabhan (1981) Asymmetric total synthesis of erythromycin. 3. Total synthesis of erythromycin. In: Journal of the American Chemical Society, 103 (11). 3215 -3217. |
| Publicador |
American Chemical Society |
| Relação |
http://pubs.acs.org/doi/abs/10.1021/ja00401a051?prevSearch=Asymmetric%2Btotal%2Bsynthesis%2Bof%2Berythromycin.%2B2.%2BSynthesis%2Bof%2Ban%2Berythronolide%2BA%2Blactone%2Bsystem&searchHistoryKey= http://eprints.iisc.ernet.in/25681/ |
| Palavras-Chave | #Molecular Biophysics Unit |
| Tipo |
Editorials/Short Communications PeerReviewed |
