Feedback-type inhibition of activity of 3-hydroxy-3-methylglutaryl coenzyme a reductase by ubiquinone
| Data(s) |
15/05/1992
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|---|---|
| Resumo |
Accompanying the decrease in serum cholesterol and increase in concentration of ubiquinone in liver and its microsomes, the activity, but not the protein, of HMG-CoA reductase decreased in ubiquinone-supplemented rats. A soluble 58-kDa preparation of HMG-CoA reductase was partially inhibited on addition of ubiquinone indicating a possible feedback type of action. |
| Formato |
application/pdf |
| Identificador |
http://eprints.iisc.ernet.in/24625/1/pdf.pdf Omkumar, RV and Gaikwad, Amos S and Ramasarma, T (1992) Feedback-type inhibition of activity of 3-hydroxy-3-methylglutaryl coenzyme a reductase by ubiquinone. In: Biochemical and Biophysical Research Communications, 184 (3). pp. 1280-1287. |
| Publicador |
Elsevier Science |
| Relação |
http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6WBK-4G0VTNW-1D8&_user=512776&_rdoc=1&_fmt=&_orig=search&_sort=d&_docanchor=&view=c&_acct=C000025298&_version=1&_urlVersion=0&_userid=512776&md5=99ac00b565efe744d549659137782e7d http://eprints.iisc.ernet.in/24625/ |
| Palavras-Chave | #Biochemistry |
| Tipo |
Journal Article PeerReviewed |
