Inhibitory action of norepinephrine on the induction of tryptophan-2,3-dioxygenase by cortisol: Mediation by the I-receptor


Autoria(s): Sitaraman, V; Ramasarma, T
Data(s)

01/05/1975

Resumo

Induction of hepatic tryptophan-2,3-dioxygenase in rats by cortisol or corticosterone was inhibited on treatment with norepinephrine. The I-adrenergic blockers showed a small potentiating effect of the norepinephrine-mediated inhibition. The I-adrenergic blockers significantly reversed this inhibition, suggesting that norepinephrine acts Image the I-receptor in inhibition of the cortisol-mediated induction of this enzyme.

Formato

application/pdf

Identificador

http://eprints.iisc.ernet.in/24105/1/http___www.sciencedirect.com_science__ob%3DMImg%26_imagekey%3DB6T99-478B24N-1BW-1%26_cdi%3D5109%26_user%3D512776%26_orig%3Dsearch%26_coverDate%3D05%252F01%252F1975%26_sk%3D999839990%26view%3Dc%26wchp%3DdGLbVlz-zSkzV%26md5%3D10fdee1efe88le.pdf

Sitaraman, V and Ramasarma, T (1975) Inhibitory action of norepinephrine on the induction of tryptophan-2,3-dioxygenase by cortisol: Mediation by the I-receptor. In: Life Sciences, 16 (9). pp. 1387-1392.

Publicador

Elsevier Science

Relação

http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T99-478B24N-1BW&_user=512776&_rdoc=1&_fmt=&_orig=search&_sort=d&_docanchor=&view=c&_acct=C000025298&_version=1&_urlVersion=0&_userid=512776&md5=d77b2b530e17b4e464bd6122c268e631

http://eprints.iisc.ernet.in/24105/

Palavras-Chave #Biochemistry
Tipo

Journal Article

PeerReviewed