Studies in metal-ammonia reduction. Part 4. Reduction and reductive methylation of 7-methoxy-3,4-dihydrophenanthren-1(2H)-one and 7-methoxy-1,2-dihydrophenanthren-4(3H)-one


Autoria(s): Rao, GSR Subba; Sundar, N Shyama
Data(s)

1982

Resumo

Birch reduction and reductive methylations of the title compounds have been investigated. 7-Methoxy-3,4-dihydrophenanthren-1(2H)-one (2) yields the cis-3,4,9,10,11,12-hexahydro-derivative (15) while the 7-methoxy-1,2-dihydrophenanthren-4(3H)-one (5) is reduced to the corresponding 1,2,9,10-tetrahydro-derivative (7). The factors influencing the mechanism of the reduction process have been discussed. The reductive methylation products of the ketone (2) are useful substrates in the synthesis of 9-methyl steroids.

Formato

application/pdf

Identificador

http://eprints.iisc.ernet.in/23086/1/fultext1.pdf

Rao, GSR Subba and Sundar, N Shyama (1982) Studies in metal-ammonia reduction. Part 4. Reduction and reductive methylation of 7-methoxy-3,4-dihydrophenanthren-1(2H)-one and 7-methoxy-1,2-dihydrophenanthren-4(3H)-one. In: Perkin Transactions 1, 6 . pp. 1381-1384.

Publicador

RSC Publishing

Relação

http://www.rsc.org/publishing/journals/P1/article.asp?doi=p19820001381

http://eprints.iisc.ernet.in/23086/

Palavras-Chave #Organic Chemistry
Tipo

Journal Article

PeerReviewed