Small local variations in B-form DNA lead to a large variety of global geometries which can accommodate most DNA-binding protein motifs
Data(s) |
24/04/2009
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Resumo |
An important question of biological relevance is the polymorphism of the double-helical DNA structure in its free form, and the changes that it undergoes upon protein-binding. We have analysed a database of free DNA crystal structures to assess the inherent variability of the free DNA structure and have compared it with a database of protein-bound DNA crystal structures to ascertain the protein-induced variations. |
Formato |
application/pdf |
Identificador |
http://eprints.iisc.ernet.in/21141/1/17.pdf Marathe, Arvind and Karandur, Deepti and Bansal, Manju (2009) Small local variations in B-form DNA lead to a large variety of global geometries which can accommodate most DNA-binding protein motifs. In: BMC Structural Biology, 9 (24). |
Publicador |
BioMed Central |
Relação |
http://www.biomedcentral.com/1472-6807/9/24 http://eprints.iisc.ernet.in/21141/ |
Palavras-Chave | #Molecular Biophysics Unit |
Tipo |
Journal Article PeerReviewed |