Physostigmine for promethazine poisoning


Autoria(s): Cleghorn, Geoffrey; Bourke, Geoffrey
Data(s)

16/08/1980

Resumo

Experience suggests that the central anticholinergic action of promethazine is a major element in the toxic effects following overdosage. Physostigmine seems to be a direct antidote at doses within the safe therapeutic range; side-effects, if they become a problem, can be treated with intravenous atropine.

Identificador

http://eprints.qut.edu.au/90931/

Publicador

The Lancet Publishing Group

Relação

http://www.download.thelancet.com/journals/lancet/article/PIIS0140-6736%2880%2990366-9/fulltext

DOI:10.1016/S0140-6736(80)90366-9

Cleghorn, Geoffrey & Bourke, Geoffrey (1980) Physostigmine for promethazine poisoning. The Lancet, 2(8190), pp. 368-369.

Fonte

Faculty of Health; Institute of Health and Biomedical Innovation; School of Exercise & Nutrition Sciences

Palavras-Chave #antidote #atropine #imipramine #ipecac #neostigmine #physostigmine #promethazine #adverse drug reaction #ataxia #case report #central nervous system #child #delirium #drug intoxication #hallucination #intoxication #intravenous drug administration #preschool child #school child #slurred speech #therapy #Child #Preschool #Female #Human #Parasympatholytics
Tipo

Journal Article