Physostigmine for promethazine poisoning
Data(s) |
16/08/1980
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Resumo |
Experience suggests that the central anticholinergic action of promethazine is a major element in the toxic effects following overdosage. Physostigmine seems to be a direct antidote at doses within the safe therapeutic range; side-effects, if they become a problem, can be treated with intravenous atropine. |
Identificador | |
Publicador |
The Lancet Publishing Group |
Relação |
http://www.download.thelancet.com/journals/lancet/article/PIIS0140-6736%2880%2990366-9/fulltext DOI:10.1016/S0140-6736(80)90366-9 Cleghorn, Geoffrey & Bourke, Geoffrey (1980) Physostigmine for promethazine poisoning. The Lancet, 2(8190), pp. 368-369. |
Fonte |
Faculty of Health; Institute of Health and Biomedical Innovation; School of Exercise & Nutrition Sciences |
Palavras-Chave | #antidote #atropine #imipramine #ipecac #neostigmine #physostigmine #promethazine #adverse drug reaction #ataxia #case report #central nervous system #child #delirium #drug intoxication #hallucination #intoxication #intravenous drug administration #preschool child #school child #slurred speech #therapy #Child #Preschool #Female #Human #Parasympatholytics |
Tipo |
Journal Article |