Metabolism of 1,8-Cineole in Rat: Its Effects on Liver and Lung Microsomal Cytochrome P-450 Systems


Autoria(s): Madyastha, KMadhava; Chadha, Anju
Data(s)

01/11/1986

Resumo

The monoterpene cyclic ether, cineole (l,8-cineole, I) also known as eucalyptol, is a component of many essential oils and is widely distributed in nature. It is extensively used in pharmaceutical preparations for external application and also as a nasal spray. It was reported earlier that cineole when administered to sheep may be largely oxidized in the system (Scheline 1978). However the mode of metabolism of cineole is not known. Hence the present study was undertaken to investigate the metabolic fate of this ubiquitous terpenoid following its administration to rats by gastric intubation.

Formato

application/pdf

Identificador

http://eprints.iisc.ernet.in/20859/1/fulltext.pdf

Madyastha, KMadhava and Chadha, Anju (1986) Metabolism of 1,8-Cineole in Rat: Its Effects on Liver and Lung Microsomal Cytochrome P-450 Systems. In: Bulletin of Environmental Contamination and Toxicology, 37 (5). 759 -766.

Publicador

Springer

Relação

http://www.springerlink.com/content/hqt07334v32j1283/

http://eprints.iisc.ernet.in/20859/

Palavras-Chave #Organic Chemistry
Tipo

Journal Article

PeerReviewed