Development of a novel experimental model to investigate the influence of mechanics on bone healing


Autoria(s): Tufekci, Pelin Melisa
Data(s)

2015

Resumo

This dissertation proposed a novel experimental model combining a defect configuration with an active instrumented fixation device to investigate the influence of mechanics on bone healing. The proposed defect configuration aimed to minimise physiological loading within an experimental fracture gap and the instrumented fixator was used for the application of controlled displacements and in vivo stiffness monitoring of the healing process. This thesis has provided a novel approach to advance current knowledge and understanding of mechanobiology, which has been limited in previous experimental models.

Formato

application/pdf

Identificador

http://eprints.qut.edu.au/90730/

Publicador

Queensland University of Technology

Relação

http://eprints.qut.edu.au/90730/1/Pelin_Tufekci_Thesis.pdf

Tufekci, Pelin Melisa (2015) Development of a novel experimental model to investigate the influence of mechanics on bone healing. PhD thesis, Queensland University of Technology.

Fonte

School of Chemistry, Physics & Mechanical Engineering; Institute of Health and Biomedical Innovation; Science & Engineering Faculty

Palavras-Chave #Fracture healing #Mechanobiology #Ovine model #Mechanical stimulation #External stimulation #Interfragmentary movement #Osteotomy #Animal model
Tipo

Thesis