Tissue engineering of a morphologically and functionally intact humanized bone organ for bone metastasis research
| Data(s) |
2015
|
|---|---|
| Resumo |
The aim of this thesis was to establish an individualized, patient-specific diagnostic and therapeutic preclinical disease model for bone metastasis research. Tissue engineering of humanized bone within mice allowed the development of a humanized immune system in the host animal. This novel platform makes it possible to analyze the growth of human cancer cells in human bone in the presence of human immune cells. |
| Formato |
application/pdf |
| Identificador | |
| Publicador |
Queensland University of Technology |
| Relação |
http://eprints.qut.edu.au/84810/1/Boris%20Michael_Holzapfel_Thesis.pdf Holzapfel, Boris Michael (2015) Tissue engineering of a morphologically and functionally intact humanized bone organ for bone metastasis research. PhD by Publication, Queensland University of Technology. |
| Fonte |
School of Biomedical Sciences; Faculty of Health; Institute of Health and Biomedical Innovation |
| Palavras-Chave | #Tissue Engineering #Bone Metastasis #Cancer Model #Haematopoiesis #Bone Microenvironment #Tumour |
| Tipo |
Thesis |
