Defining a 3-dimensional (3D) in vitro model to study immune cell and renal cell interactions


Autoria(s): Afrin, Sadia
Data(s)

2015

Resumo

This study aimed to develop a 3-Dimensional (D) hydrogel system for the co-culture of autologous human renal and immune cells. Previous studies have shown that human renal epithelial cells are able to modulate autologous immune cell responses. However, these studies were undertaken in a standard 2D culture system. The 3D model was developed to re-capitulate these observations within a more physiological relevant in vivo like environment.

Formato

application/pdf

Identificador

http://eprints.qut.edu.au/84754/

Publicador

Queensland University of Technology

Relação

http://eprints.qut.edu.au/84754/1/Sadia_Afrin_Thesis.pdf

Afrin, Sadia (2015) Defining a 3-dimensional (3D) in vitro model to study immune cell and renal cell interactions. Masters by Research thesis, Queensland University of Technology.

Fonte

School of Chemistry, Physics & Mechanical Engineering; Institute of Health and Biomedical Innovation; Science & Engineering Faculty

Palavras-Chave #3D in vitro model #Hydrogels #Immune modulation #Proximal tubule epithelial cells #T lymphocytes
Tipo

Thesis