Development of an evidence-based symptom checklist for symptoms of recurrence in women with endometrial cancer
Data(s) |
2015
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Resumo |
Objective Women treated for endometrial cancer currently commonly attend clinic-based follow-up examinations for up to five years. This is based on little evidence and alternative models need to be investigated. This study aimed to identify currently available symptom checklists, determine the comprehensiveness of identified checklists, and generate an updated list of symptoms potentially associated with a recurrence of endometrial cancer for future testing within a prospective study. Methods/materials We conducted a systematic review of the literature extracting; routine follow-up schedules; proportion of patients with symptomatic or asymptomatic recurrence; symptoms of recurrence; prevalence of these symptoms at recurrence. Results Overall, three previous checklists, and 12 retrospective studies were identified meeting the selection criteria. The average rate of recurrence across the studies was 13% (range 3%-19%). The proportion of patients identified with a symptomatic recurrence varied widely (overall average 67%;range 41% to 91%). The most commonly reported symptoms were vaginal bleeding (25%), pain [not further described] (16%) and abdominal pain and/or discomfort and swelling (15%) which combined, represented 56% of the total reported symptoms. The three previous checklists listed 14 and this review identified an additional 24 symptoms (e.g. vaginal discharge, leg pain, constipation, headache and self-detected mass) not previously identified. Conclusion The newly developed symptom checklist expands previous ones, by an additional 24 symptoms. It will be used in a prospective cohort study to assess whether it is sensitive and specific enough to identify recurrence compared to current standard follow-up examinations. |
Formato |
application/pdf |
Identificador | |
Publicador |
cancer-research-frontiers.org |
Relação |
http://eprints.qut.edu.au/81862/3/81862.pdf http://cancer-research-frontiers.org/wp-content/uploads/2015/03/CRF-2015-1-75-1.pdf de Witt, Audra, Janda, Monika, & Obermair, Andreas (2015) Development of an evidence-based symptom checklist for symptoms of recurrence in women with endometrial cancer. Cancer Research Frontiers, 1(1), pp. 75-88. http://purl.org/au-research/grants/NHMRC/1045247 |
Direitos |
Copyright 2015 The Authors |
Fonte |
Faculty of Health; Institute of Health and Biomedical Innovation; School of Public Health & Social Work |
Palavras-Chave | #110000 MEDICAL AND HEALTH SCIENCES #111700 PUBLIC HEALTH AND HEALTH SERVICES #anzsrc Australian and New Zealand Standard Research Class #endometrial cancer #symptom checklist #recurrence #follow-up care #institutional follow-up protocol |
Tipo |
Journal Article |