Mathematical modelling of intramembranous bone formation during fracture healing


Autoria(s): Manitzky, Louise J.
Data(s)

2014

Resumo

During fracture healing, many complex and cryptic interactions occur between cells and bio-chemical molecules to bring about repair of damaged bone. In this thesis two mathematical models were developed, concerning the cellular differentiation of osteoblasts (bone forming cells) and the mineralisation of new bone tissue, allowing new insights into these processes. These models were mathematically analysed and simulated numerically, yielding results consistent with experimental data and highlighting the underlying pattern formation structure in these aspects of fracture healing.

Formato

application/pdf

Identificador

http://eprints.qut.edu.au/78983/

Publicador

Queensland University of Technology

Relação

http://eprints.qut.edu.au/78983/1/Louise_Manitzky_Thesis.pdf

Manitzky, Louise J. (2014) Mathematical modelling of intramembranous bone formation during fracture healing. PhD thesis, Queensland University of Technology.

Fonte

Institute of Health and Biomedical Innovation; School of Mathematical Sciences; Science & Engineering Faculty

Palavras-Chave #Fracture Healing #Intramembranous Bone Formation #Mathematical Modelling #Mineralisation #Osteoblast differentiation #Turing Patterns
Tipo

Thesis