Saliva as an emerging biofluid for clinical diagnosis and applications of MEMS/NEMS in salivary diagnostics
Contribuinte(s) |
Subramani, K. Ahmed, W. Hartsfield, J. K. |
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Data(s) |
14/12/2012
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Resumo |
Saliva as a biological fluid is gaining wider acceptance for diagnosing diseases. The growing interest in saliva as a biological fluid is due to its noninvasiveness, ease of use, cost-effectiveness, and multiple sample collection possibilities as well as minimal risk to health care professionals of contracting infectious organisms such as HIV and Hep B. However, the clinical translation of saliva is hampered by our lack of understanding of the biomolecular transportation from blood into saliva, the diurnal variations of biomolecules present in saliva, and relatively low levels of analytes (100th to a 1000th fold less than in blood). We provide information on the current status of salivary research, salivary diagnostics empowered by nanotechnology, and future prospects in this emerging field of saliva diagnostics. |
Identificador | |
Publicador |
William Andrew [Elsevier] |
Relação |
http://www.sciencedirect.com/science/article/pii/B9781455731275000222# DOI:10.1016/B978-1-4557-3127-5.00022-2 Punyadeera, Chamindie & Slowey, Paul D. (2012) Saliva as an emerging biofluid for clinical diagnosis and applications of MEMS/NEMS in salivary diagnostics. In Subramani, K., Ahmed, W., & Hartsfield, J. K. (Eds.) Nanobiomaterials in Clinical Dentistry. William Andrew [Elsevier], Oxford , UK, pp. 453-473. |
Direitos |
Copyright © 2013 Elsevier Inc. All rights reserved |
Fonte |
School of Biomedical Sciences; Faculty of Health; Institute of Health and Biomedical Innovation |
Palavras-Chave | #c-reactive protein #squamous-cell carcinoma #proteomic analysis #anxiety #disorders #plasma proteomes #dna methylation #neck-cancer #oral fluid #flow-rate #biomarkers |
Tipo |
Book Chapter |