DNA binding study of isophorone in rats and mice
Data(s) |
01/11/1990
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Resumo |
Following isophorone exposure, in a 2-year study with F344 rats and B6C3F1 mice performed under the National Toxicology Program (NTP), an elevated incidence of tumors was observed in male rats (kidney tumors) and male mice (liver tumors). Female rats and mice showed no elevation of tumor rates by isophorone (NTP 1986). |
Identificador | |
Publicador |
Springer |
Relação |
DOI:10.1007/BF01974699 Thier, R., Peter, H., Wiegand, H. J., & Bolt, H. M. (1990) DNA binding study of isophorone in rats and mice. Archives of Toxicology, 64(8), pp. 684-685. |
Direitos |
Copyright 1990 Springer |
Fonte |
School of Clinical Sciences; Faculty of Health |
Palavras-Chave | #isophorone #animal experiment #animal tissue #dna binding #female #kidney #letter #liver #male #mouse #nonhuman #priority journal #rat #sex difference #Animal #Cyclohexanones #DNA #Mice #Rats #Rats #Inbred F344 #Animalia |
Tipo |
Journal Article |