DNA binding study of isophorone in rats and mice


Autoria(s): Thier, R.; Peter, H.; Wiegand, H. J.; Bolt, H. M.
Data(s)

01/11/1990

Resumo

Following isophorone exposure, in a 2-year study with F344 rats and B6C3F1 mice performed under the National Toxicology Program (NTP), an elevated incidence of tumors was observed in male rats (kidney tumors) and male mice (liver tumors). Female rats and mice showed no elevation of tumor rates by isophorone (NTP 1986).

Identificador

http://eprints.qut.edu.au/77493/

Publicador

Springer

Relação

DOI:10.1007/BF01974699

Thier, R., Peter, H., Wiegand, H. J., & Bolt, H. M. (1990) DNA binding study of isophorone in rats and mice. Archives of Toxicology, 64(8), pp. 684-685.

Direitos

Copyright 1990 Springer

Fonte

School of Clinical Sciences; Faculty of Health

Palavras-Chave #isophorone #animal experiment #animal tissue #dna binding #female #kidney #letter #liver #male #mouse #nonhuman #priority journal #rat #sex difference #Animal #Cyclohexanones #DNA #Mice #Rats #Rats #Inbred F344 #Animalia
Tipo

Journal Article