Telomerase activity : detection and clinical implications in human cancer


Autoria(s): Smith, Robert A.; Lam, Alfred King-Yin
Data(s)

2009

Resumo

Telomerase is an extremely important enzyme required for the immortalisation of tumour cells. Because the gene is activated in the vast majority of tumour tissues and remains unused in most somatic cells, it represents a marker with huge diagnostic, prognostic and treatment implications in cancer. This article summarises the basic structure and functions of telomerase and considers its clinical implications in colorectal and other cancers.

Identificador

http://eprints.qut.edu.au/74635/

Publicador

Reed Business Information - Belgium

Relação

http://www98.griffith.edu.au/dspace/bitstream/handle/10072/28778/59718_1.pdf;jsessionid=0E545A374C022AC92CCB93B2EC648905?sequence=1

Smith, Robert A. & Lam, Alfred King-Yin (2009) Telomerase activity : detection and clinical implications in human cancer. Clinical Laboratory International, 2, pp. 24-27.

Direitos

Copyright 2009 Reed Business Information

Fonte

School of Biomedical Sciences; Faculty of Health; Institute of Health and Biomedical Innovation

Palavras-Chave #111203 Cancer Genetics #Telomerase #cancer #colorectal cancer #carcinoma
Tipo

Journal Article