B-Raf mutation : a key player in molecular biology of cancer
| Data(s) |
2013
|
|---|---|
| Resumo |
B-Raf is one of the more commonly mutated proto-oncogenes implicated in the development of cancers. In this review, we consider the mechanisms and clinical impacts of B-Raf mutations in cancer and discuss the implications for the patient in melanoma, thyroid cancer and colorectal cancer, where B-Raf mutations are particularly common. |
| Formato |
application/pdf |
| Identificador | |
| Publicador |
Elsevier |
| Relação |
http://eprints.qut.edu.au/74505/4/74505.pdf DOI:10.1016/j.yexmp.2013.10.005 Rahman, M.A., Salajegheh, A., Smith, R.A., & Lam, A.K. (2013) B-Raf mutation : a key player in molecular biology of cancer. Experimental and Molecular Pathology, 95(3), pp. 336-42. |
| Direitos |
Copyright 2013 Elsevier This is the author’s version of a work that was accepted for publication in Experimental and Molecular Pathology. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Experimental and Molecular Pathology, [VOL 95, ISSUE 3, (2013)] DOI: 10.1016/j.yexmp.2013.10.005 |
| Fonte |
School of Biomedical Sciences; Faculty of Health; Institute of Health and Biomedical Innovation |
| Palavras-Chave | #111203 Cancer Genetics #B-Raf #BRAF #Mutation #Melanoma #Colorectal cancer #Thyroid cancer |
| Tipo |
Journal Article |
