Executive function and postural instability in people with Parkinson’s disease


Autoria(s): Xu, Dong; Cole, Michael H.; Mengersen, Kerrie; Silburn, Peter A.; Qiu, Feng; Graepel, Cara; Kerr, Graham K.
Data(s)

28/06/2014

Resumo

The specific aspects of cognition contributing to balance and gait have not been clarified in people with Parkinson’s disease (PD). Twenty PD participants and twenty age- and gender-matched healthy controls were assessed on cognition and clinical mobility tests. General cognition was assessed with the Mini Mental State Exam and the Addenbrooke’s Cognitive Exam. Executive function was evaluated using the Trail Making Tests (TMT-A and TMT-B) and a computerized cognitive battery which included a series of choice reaction time (CRT) tests. Clinical gait and balance measures included the Tinetti, Timed Up & Go, Berg Balance and Functional Reach tests. PD participants performed significantly worse than the controls on the tests of cognitive and executive function, balance and gait. PD participants took longer on Trail Making Tests, CRT-Location and CRT-Colour (inhibition response). Furthermore, executive function, particularly longer times on CRT-Distracter and greater errors on the TMT-B were associated with worse balance and gait performance in the PD group. Measures of general cognition were not associated with balance and gait measures in either group. For PD participants, attention and executive function were impaired. Components of executive function, particularly those involving inhibition response and distracters, were associated with poorer balance and gait performance in PD.

Formato

application/pdf

Identificador

http://eprints.qut.edu.au/73483/

Publicador

Hindawi Publishing Corporation

Relação

http://eprints.qut.edu.au/73483/1/Xu_etal_ExecutiveFunction%26PosturalInstabilityInPeopleWithParkinsonsDisease.pdf

http://downloads.hindawi.com/journals/pd/aip/684758.pdf

DOI:10.1155/2014/684758

Xu, Dong, Cole, Michael H., Mengersen, Kerrie, Silburn, Peter A., Qiu, Feng, Graepel, Cara, & Kerr, Graham K. (2014) Executive function and postural instability in people with Parkinson’s disease. Parkinson's Disease, 2014, p. 684758.

PARKINSON'S QLD/PhD grant

Direitos

Copyright 2014 Hindawi Publishing Corporation

Fonte

Faculty of Health; Institute of Health and Biomedical Innovation; School of Mathematical Sciences; Science & Engineering Faculty; School of Exercise & Nutrition Sciences

Palavras-Chave #110308 Geriatrics and Gerontology #110603 Motor Control #110904 Neurology and Neuromuscular Diseases #170101 Biological Psychology (Neuropsychology Psychopharmacology Physiological Psychology) #Parkinson's disease #Cognitive function #Executive function #Balance #Gait
Tipo

Journal Article