Turtle ghrelin
Data(s) |
28/05/2014
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Resumo |
In a recent paper, Wang and colleagues described the genomes of two turtles, the Chinese soft-shell turtle (Pelodiscus sinensis) and the green sea turtle (Chelonia mydas)1. A salient finding was an apparent absence of GHRL, the gene encoding the only known circulating orexigen, the peptide hormone ghrelin. The highly conserved GHRL encodes at least two bioactive peptide hormones, ghrelin2 and obestatin3, which are recognized to have a diverse range of functions in a number of cell types and physiological systems4, 5. Wang and colleagues hypothesized that the absence of ghrelin was associated with the low metabolic rate observed in these turtle species1. |
Identificador | |
Publicador |
Nature Publishing Group |
Relação |
http://www.nature.com/ng/journal/v46/n6/pdf/ng.2964.pdf DOI:10.1038/ng.2964 Seim, Inge, Jeffery, Penelope, Herington, Adrian, & Chopin, Lisa (2014) Turtle ghrelin. Nature Genetics, 46(6), pp. 525-526. |
Fonte |
School of Biomedical Sciences; Faculty of Health; Institute of Health and Biomedical Innovation |
Palavras-Chave | #060300 EVOLUTIONARY BIOLOGY #060309 Phylogeny and Comparative Analysis #060400 GENETICS #119999 Medical and Health Sciences not elsewhere classified #ghrelin #transcriptomics #genomics #endocrinology |
Tipo |
Journal Article |