Simultaneous magnetic resonance imaging and consolidation measurement of articular cartilage


Autoria(s): Wellard, R. Mark; Ravasio, Jean-Phillippe; Guesne, Samuel; Bell, Christopher; Oloyede, Adekunle; Tevelan, Greg; Pope, James M.; Momot, Konstantin I.
Data(s)

01/05/2014

Resumo

Magnetic resonance imaging (MRI) offers the opportunity to study biological tissues and processes in a non-disruptive manner. The technique shows promise for the study of the load-bearing performance (consolidation) of articular cartilage and changes in articular cartilage accompanying osteoarthritis. Consolidation of articular cartilage involves the recording of two transient characteristics: the change over time of strain and the hydrostatic excess pore pressure (HEPP). MRI study of cartilage consolidation under mechanical load is limited by difficulties in measuring the HEPP in the presence of the strong magnetic fields associated with the MRI technique. Here we describe the use of MRI to image and characterize bovine articular cartilage deforming under load in an MRI compatible consolidometer while monitoring pressure with a Fabry-Perot interferometer-based fiber-optic pressure transducer.

Formato

application/pdf

Identificador

http://eprints.qut.edu.au/71096/

Publicador

MDPI AG

Relação

http://eprints.qut.edu.au/71096/2/71096.pdf

http://www.mdpi.com/1424-8220/14/5/7940

DOI:10.3390/s140507940

Wellard, R. Mark, Ravasio, Jean-Phillippe, Guesne, Samuel, Bell, Christopher, Oloyede, Adekunle, Tevelan, Greg, Pope, James M., & Momot, Konstantin I. (2014) Simultaneous magnetic resonance imaging and consolidation measurement of articular cartilage. Sensors, 14(5), pp. 7940-7958.

http://purl.org/au-research/grants/ARC/DP0880346

Direitos

Copyright 2014 MDPI AG

Fonte

School of Biomedical Sciences; School of Chemistry, Physics & Mechanical Engineering; Institute of Health and Biomedical Innovation; Science & Engineering Faculty

Palavras-Chave #060000 BIOLOGICAL SCIENCES #111600 MEDICAL PHYSIOLOGY #119900 OTHER MEDICAL AND HEALTH SCIENCES #fiber interferometers #magnetic resonance imaging #compression #collagen structure #consolidometery
Tipo

Journal Article