Double trouble — the art of synthesis of chiral dimeric natural products


Autoria(s): Wezeman, Tim; Masters, Kye-Simeon; Brase, Stefan
Data(s)

03/04/2014

Resumo

Double or nothing! Recently the total ynthesis of secalonic acids A and D was reported. This work and other natural product syntheses with a dimerization step as a common feature are featured in this highlight. The significant biological activity of the secalonic acids and the fact that their synthesis has fascinated synthetic chemists for the past forty years make this work a milestone in natural product synthesis.

Identificador

http://eprints.qut.edu.au/69896/

Publicador

Wiley - V C H Verlag GmbH & Co. KGaA

Relação

http://onlinelibrary.wiley.com/doi/10.1002/anie.201402384/pdf

DOI:10.1002/anie.201402384

Wezeman, Tim, Masters, Kye-Simeon, & Brase, Stefan (2014) Double trouble — the art of synthesis of chiral dimeric natural products. Angewandte Chemie International Edition, 53(18), pp. 4524-4526.

Direitos

Coppyright 2014 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

Fonte

School of Chemistry, Physics & Mechanical Engineering; Science & Engineering Faculty

Palavras-Chave #030500 ORGANIC CHEMISTRY #030502 Natural Products Chemistry #030503 Organic Chemical Synthesis #Diels–Alder reactions #dimerization #natural products #oxidative coupling #secalonic acid
Tipo

Journal Article