An efficient synthesis of (±)-frondosin B using a Stille–Heck reaction sequence
| Data(s) |
19/01/2010
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|---|---|
| Resumo |
A concise, convergent synthesis of (±)-frondosin B has been developed based on the application of a Stille–Heck reaction sequence of 2-chloro-5-methoxybenzo[b]furan-3-yl triflate and 2-(3-butenyl)-3-(trimethylstannyl)cyclohex-2-enone giving the racemic natural product in a 34% overall yield. |
| Formato |
application/pdf |
| Identificador | |
| Publicador |
Royal Society of Chemistry |
| Relação |
http://eprints.qut.edu.au/69693/1/b924542a.pdf DOI:10.1039/B924542A Masters, Kye-Simeon & Flynn, Bernard L. (2010) An efficient synthesis of (±)-frondosin B using a Stille–Heck reaction sequence. Organic & Biomolecular Chemistry, 8(6), pp. 1290-1292. |
| Direitos |
Copyright 2010 Royal Society of Chemistry Reproduced by permission of The Royal Society of Chemistry, no further distribution permitted. |
| Fonte |
School of Chemistry, Physics & Mechanical Engineering; Science & Engineering Faculty |
| Palavras-Chave | #030502 Natural Products Chemistry #030503 Organic Chemical Synthesis |
| Tipo |
Journal Article |
