The acetal concept : regioselective access toortho,ortho-diphenols via dibenzo-1,3-dioxepines
Data(s) |
23/11/2013
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Resumo |
Traditional methods are ill-suited for the synthesis of ortho,ortho-biphenols, a structural motif found in many polyphenolic natural products, as well as synthetically useful compounds such as the chiral ligands binol, vapol, and vanol. The new route consists of a radical-based reaction of an acetal-tethered biphenyl ether substrate and subsequent hydrolytic cleavage of the dibenzo-1,3-dioxepine intermediate. |
Identificador | |
Publicador |
John Wiley & Sons Inc |
Relação |
DOI:10.1002/anie.201207485 Masters, Kye-Simeon & Bräse, Stefan (2013) The acetal concept : regioselective access toortho,ortho-diphenols via dibenzo-1,3-dioxepines. Angewandte Chemie International Edition, 52(3), pp. 866-869. |
Direitos |
Copyright 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim |
Fonte |
School of Chemistry, Physics & Mechanical Engineering; Science & Engineering Faculty |
Palavras-Chave | #030503 Organic Chemical Synthesis |
Tipo |
Journal Article |