Comparing skin biopsy with confocal microscopy : diagnostic yield of nerve fiber density
Data(s) |
01/09/2010
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Resumo |
Background and aims: The assessment of intra-epidermal nerve fiber density (IENFD) in skin biopsies and corneal nerve fiber density (CNFD) using corneal confocal microscopy (CCM) provides promising techniques to detect small nerve fiber damage in patients with peripheral neuropathy. To help define the clinical utility of each of these techniques in patients with diabetic neuropathy we have assessed sensitivity and specificity of IENFD and CNFD in predicting the following: 1) diabetic polyneuropathy (DPN); 2) risk of foot ulceration (RFU); 3) initial small fiber neuropathy (iSFN); 4) severe small fiber neuropathy (sSFN)... |
Identificador | |
Publicador |
Springer Verlag |
Relação |
DOI:10.1007/s00125-010-1872-z Quattrini, Christian, Tavakoli, Mitra, Kallinikos, Panagiotis A., Marshall, Alison L., Efron, Nathan, Boulton, Andrew J.M., & Malik, Rayaz A. (2010) Comparing skin biopsy with confocal microscopy : diagnostic yield of nerve fiber density. Diabetologia, 53(Supp 1), p. 1114. |
Fonte |
Faculty of Health; Institute of Health and Biomedical Innovation; School of Optometry & Vision Science |
Palavras-Chave | #111300 OPTOMETRY AND OPHTHALMOLOGY |
Tipo |
Journal Article |