Direct iodination of isoindolines and isoindoline nitroxides as precursors to functionalized nitroxides
| Data(s) |
2013
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|---|---|
| Resumo |
A new method for the direct aryl iodination of isoindolines and isoindoline nitroxides which utilizes periodic acid and potassium iodide in sulfuric acid is presented. Di-iodo functionalized tetramethyl and tetraethyl isoindolines and a di-iodo tetramethyl isoindoline nitroxide were prepared in high yield (70-82%). The analogous mono-iodo species were afforded in modest yield (34-48%). Iodinated nitrones were also obtained from a tetraethyl isoindoline nitroxide. |
| Formato |
application/pdf |
| Identificador | |
| Publicador |
John Wiley & Sons |
| Relação |
http://eprints.qut.edu.au/66645/2/66645.pdf DOI:10.1002/ejoc.201300313 Fairfull-Smith, Kathryn E., Debele, Emmanuel, Allen, Jesse, Prfunder, Michael, & McMurtrie, John (2013) Direct iodination of isoindolines and isoindoline nitroxides as precursors to functionalized nitroxides. European Journal of Organic Chemistry, 2013(22), pp. 4829-4835. |
| Direitos |
Copyright 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim |
| Fonte |
School of Chemistry, Physics & Mechanical Engineering; Faculty of Science and Technology; Science & Engineering Faculty |
| Palavras-Chave | #030000 CHEMICAL SCIENCE #Synthetic methods #Aromatic substitution #Halogenation #radicals #Nitrogen oxides |
| Tipo |
Journal Article |
