Hospitalisation of Indigenous children in the Northern Territory for lower respiratory illness in the first year of life
Data(s) |
2010
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Resumo |
Objective To describe the epidemiology of acute lower respiratory infection (ALRI) and bronchiectasis in Northern Territory Indigenous infants hospitalised in the first year of life. Design A historical cohort study constructed from the NT Hospital Discharge Dataset and the NT Imm(u)nisation Register. Participants and setting All NT resident Indigenous infants, born 1 January 1999 to 31 December 2004, admitted to NT public hospitals and followed up to 12 months of age. Main outcome measures Incidence of ALRI and bronchiectasis (ICD-10-AM codes) and radiologically confirmed pneumonia (World Health Organization protocol). Results Data on 9295 infants, 8498 child-years of observation and 15 948 hospitalised episodes of care were analysed. ALRI incidence was 426.7 episodes per 1000 child-years (95% Cl, 416.2-437.2). Incidence rates were two times higher (relative risk, 2.12; 95% Cl, 1.98-2.27) for infants in Central Australia compared with those in the Top End. The median age at first admission for an ALRI was 4.6 months (interquartile range, 2.6-7.3). Bronchiolitis accounted for most of the disease burden, with a rate of 227 per 1000 child-years. The incidence of first diagnosis of bronchiectasis was 1.18 per 1000 child-years (95% Cl, 0.60-2.16). One or more key comorbidities were present in 1445 of the 3227 (44.8%) episodes of care for ALRI. Conclusions Rates of ALRI and bronchiectasis in NT Indigenous infants are excessive, with early onset, frequent repeat episodes, and a high prevalence of comorbidities. These high rates of disease demand urgent attention. |
Identificador | |
Publicador |
Australasian Medical Publishing Company Ltd |
Relação |
https://www.mja.com.au/journal/2010/192/10/hospitalisation-indigenous-children-northern-territory-lower-respiratory-illness O'Grady, Kerry-Ann, Torzillo, Paul J., & Chang, Anne M. (2010) Hospitalisation of Indigenous children in the Northern Territory for lower respiratory illness in the first year of life. Medical Journal of Australia, 192(10), pp. 586-590. http://purl.org/au-research/grants/NHMRC/359341 |
Fonte |
Faculty of Health |
Palavras-Chave | #pneumococcal conjugate vaccine #radiologically-confirmed pneumonia #placebo-controlled-trial #aboriginal children #childhood pneumonia #central australia #double-blind #infections #age #efficacy |
Tipo |
Journal Article |