Pharmacogenetics of migraine : genetic variants and their potential role in migraine therapy


Autoria(s): Fernandez, Francesca; Colson, N. J.; Griffiths, Lyn R.
Data(s)

2007

Resumo

Migraine is a paroxysmal neurological disorder affecting up to 6% of males and 18% of females in the general population, and has been demonstrated to have a strong, but complex, genetic component. Genetic investigation of migraine provides hope that new targets for medications and individual specific therapy will be developed. The identification of polymorphisms or genetic biomarkers for disease susceptibility and treatment should aid in providing a better understanding of migraine pathology and, consequently, more appropriate and efficient treatment for migraineurs. In this review, we will discuss results investigating genetic biomarkers for migraine and their potential role in future therapy planning.

Identificador

http://eprints.qut.edu.au/62695/

Publicador

Future Medicine Ltd.

Relação

DOI:10.2217/14622416.8.6.609

Fernandez, Francesca, Colson, N. J., & Griffiths, Lyn R. (2007) Pharmacogenetics of migraine : genetic variants and their potential role in migraine therapy. Pharmacogenomics, 8(6), pp. 609-622.

Direitos

Copyright 2007 Future Medicine Ltd.

Fonte

Institute of Health and Biomedical Innovation

Tipo

Journal Article