Mathematical modelling of tumour growth and interaction with host tissue and the immune system


Autoria(s): Trisilowati,
Data(s)

2013

Resumo

In this thesis, three mathematical models describing the growth of solid tumour incorporating the host tissue and the immune system response are developed and investigated. The initial model describes the dynamics of the growing tumour and immune response before being extended in the second model by introducing a time-varying dendritic cell-based treatment strategy. Finally, in the third model, we present a mathematical model of a growing tumour using a hybrid cellular automata. These models can provide information to pre-experimental work to assist in designing more effective and efficient laboratory experiments related to tumour growth and interactions with the immune system and immunotherapy.

Formato

application/pdf

Identificador

http://eprints.qut.edu.au/61133/

Publicador

Queensland University of Technology

Relação

http://eprints.qut.edu.au/61133/5/Trisilowati_Thesis.pdf

Trisilowati, (2013) Mathematical modelling of tumour growth and interaction with host tissue and the immune system. PhD thesis, Queensland University of Technology.

Fonte

Institute of Health and Biomedical Innovation; School of Mathematical Sciences; Science & Engineering Faculty

Palavras-Chave #tumour #immune #differential equation #cellular automata #optimal control #dendritic cells #natural killer cells #cytotoxic T cells
Tipo

Thesis