Designed biodegradable hydrogel structures prepared by stereolithography using poly(ethylene glycol)/poly(D,L-lactide)-based resins
Data(s) |
20/11/2010
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Resumo |
Designed three-dimensional biodegradable poly(ethylene glycol)/poly(D,L-lactide) hydrogel structures were prepared for the first time by stereolithography at high resolutions. A photopolymerisable aqueous resin comprising PDLLA-PEG-PDLLA-based macromer, visible light photo-initiator, dye and inhibitor in DMSO/water was used to build the structures. Porous and non-porous hydrogels with well-defined architectures and good mechanical properties were prepared. Porous hydrogel structures with a gyroid pore network architecture showed narrow pore size distributions, excellent pore interconnectivity and good mechanical properties. The structures showed good cell seeding characteristics, and human mesenchymal stem cells adhered and proliferated well on these materials. |
Formato |
application/pdf |
Identificador | |
Publicador |
Elsevier |
Relação |
http://eprints.qut.edu.au/38862/1/c38862.pdf DOI:10.1016/j.jconrel.2010.07.111 Seck, Tetsu M., Melchels, Ferry P.W., Feijen, Jan, & Grijpma, Dirk W. (2010) Designed biodegradable hydrogel structures prepared by stereolithography using poly(ethylene glycol)/poly(D,L-lactide)-based resins. Journal of Controlled Release, 148(1), pp. 34-41. |
Direitos |
Copyright 2010 Elsevier B.V. All rights reserved. |
Fonte |
Faculty of Built Environment and Engineering; Institute of Health and Biomedical Innovation; School of Engineering Systems |
Palavras-Chave | #090301 Biomaterials #Biodegradable hydrogels #designed porous structures #stereolithography #macromer photopolymerisation #tissue engineering |
Tipo |
Journal Article |