Age-related development of a refractive index plateau in the human lens : evidence for a distinct nucleus
Data(s) |
14/01/2008
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Resumo |
The human lens comprises two distinct regions in which the refractive index changes at different rates. The periphery contains a rapidly increasing refractive index gradient, which becomes steeper with age. The inner region contains a shallow gradient, which flattens with age, due to formation of a central plateau, of RI = 1.418, which reaches a maximum size of 7.0 × 3.05 mm around age 60 years. Formation of the plateau can be attributed to compression of fibre cells generated in prenatal life. Present in prenatal but not in postnatal fibre cells, γ-crystallin may play a role in limiting nuclear cell compression. |
Formato |
application/pdf |
Identificador | |
Publicador |
Optometrists Association Australia |
Relação |
http://eprints.qut.edu.au/29067/1/c29067.pdf DOI:10.1111/j.1444-0938.2007.00244.x Augusteyn, Robert C., Jones, Catherine E., & Pope, James M. (2008) Age-related development of a refractive index plateau in the human lens : evidence for a distinct nucleus. Clinical and Experimental Optometry, 91(3), pp. 296-301. |
Direitos |
Copyright 2008 Optometrists Association Australia The definitive version is available at www3.interscience.wiley.com |
Fonte |
Faculty of Science and Technology; School of Physical & Chemical Sciences |
Palavras-Chave | #Gradient #Lens #Growth #Nucleus #Refraction #RI Plateau |
Tipo |
Journal Article |