Incomplete pregnancy and risk of ovarian cancer : results from two Australian case-control studies and systematic review
Contribuinte(s) |
Australian Cancer Study Group (Ovarian Cancer) The Australian Ovarian Cancer Study Group |
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Data(s) |
2009
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Resumo |
Although full-term pregnancies reduce the risk of ovarian cancer, it has not been conclusively established whether incomplete pregnancies also influence risk. We investigated the relationship between a history of incomplete pregnancy and incident epithelial ovarian cancer among over 4,500 women who participated in two large Australian population-based case-control studies in 1990-1993 and 2002-2005. They provided responses to detailed questions about their reproductive histories and other personal factors. Summary odds ratios (OR) and confidence intervals (CI) derived from each study using the same covariates were aggregated. We found no significant associations between the number of incomplete pregnancies and ovarian cancer, for parous (OR = 0.98, 95% CI: 0.89, 1.08) or nulliparous (OR = 1.06, 95% CI: 0.75, 1.48) women, nor for the number of spontaneous or induced abortions and ovarian cancer for parous women (OR = 0.95, 95% CI 0.82, 1.09; OR = 1.08, 95% CI: 0.86, 1.36) or nulliparous women (OR = 1.2, 95% CI: 0.6, 2.4; OR = 0.8, 95% CI: 0.47, 1.38), respectively. A systematic review of 37 previous studies of the topic confirmed our findings that a history of incomplete pregnancy does not influence a woman’s risk of epithelial ovarian cancer. |
Formato |
application/pdf |
Identificador | |
Publicador |
Springer |
Relação |
http://eprints.qut.edu.au/28451/1/c28451.pdf DOI:10.1007/s10552-009-9402-3 Dick, Marie-Louise B., Siskind, Victor, Purdie, David M., & Green, Adele C. (2009) Incomplete pregnancy and risk of ovarian cancer : results from two Australian case-control studies and systematic review. Cancer Causes & Control, 20(9), pp. 1571-1585. |
Direitos |
Copyright 2009 Springer |
Fonte |
Centre for Accident Research & Road Safety - Qld (CARRS-Q) |
Palavras-Chave | #111706 Epidemiology #Abortion #Ovarian neoplasms #Risk #Cancer |
Tipo |
Journal Article |