Polymorphisms in the C-type lectin genes cluster in chromosome 19 and predisposition to severe acute respiratory syndrome coronavirus (SARS-CoV) infection

Background: Polymorphisms of CLEC4M have been associated with predisposition for infection by the severe acute respiratory syndrome coronavirus (SARS-CoV). DC-SIGNR, a C-type lectin encoded by CLEC4M, is a receptor for the virus. A variable number tandem

角突泥介虫(Ilyocypris angulata Sars)(介形亚纲)雄体的发现

本文报道了角突泥介虫(Ilyocypris angulata Sars)雄体的发现。对此雄体进行了详细的描述,论述了泥介虫属的生活方式,并讨论了介形类有三种生殖方式。

瘦尾细额溞Oxyurella tenuicaudis(Sars,1862)的若干生物学特征

瘦尾细额溞是一种出现数量极其稀少的枝角类。关于它的生物学特征尚未见诸文献。本文测量了一次采自云南永胜一池塘的本种300个两性个体的体长和怀卵量,就其幼体与成体的数量、体长与怀卵量、雄性以及性比等问题探讨了种群的生物学状况。 详细观察比较了这个种的重要分类特征——雌体后腹部,并描述了变异范围。对卵鞍和雄体也作了描述。

Phylogeny of SARS-CoV based on high-dimensional information geometry

We proposed a novel methodology, which firstly, extracting features from species' complete genome data, using k-tuple, followed by studying the evolutionary relationship between SARS-CoV and other coronavirus species using the method, called "High-dimensional information geometry". We also used the mothod, namely "caculating of Minimum Spanning Tree", to construct the Phyligenetic tree of the coronavirus. From construction of the unrooted phylogenetic tree, we found out that the evolution distance between SARS-CoV and other coronavirus species is comparatively far. The tree accurately rebuilt the three groups of other coronavirus. We also validated the assertion from other literatures that SARS-CoV is similar to the coronavirus species in Group I.

Determination of SARS-coronavirus by a microfluidic chip system

We have developed a new experimental system based on a microfluidic chip to determine severe acute respiratory syndrome coronavirus (SARS-Cov). The system includes a laser-induced fluorescence microfluidic chip analyzer, a glass microchip for both polymerase chain reaction (PCR) and capillary electrophoresis, a chip thermal cycler based on dual Peltier thermoelectric elements, a reverse transcription-polymerase chain reaction (RT-PCR) SARS diagnostic kit, and a DNA electrophoretic sizing kit. The system allows efficient cDNA amplification of SARS-CoV followed by electrophoretic sizing and detection on the same chip. To enhance the reliability of RT-PCR on SARS-CoV detection, duplex PCR was developed on the microchip. The assay was carried out on a home-made microfluidic chip system. The positive and the negative control were cDNA fragments of SARS-CoV and parainfluenza virus, respectively. The test results showed that 17 positive samples were obtained among 18 samples of nasopharyngeal swabs from clinically diagnosed SARS patients. However, 12 positive results from the same 18 samples were obtained by the conventional RT-PCR with agarose gel electrophoresis detection. The SARS virus species can be analyzed with high positive rate and rapidity on the microfluidic chip system.

SARS起源于污染对病毒进化的加速诱导

针对当前广为流传的SARS病毒“太空起源说”和“野生动物来源说”两种理论 ,本文根据污染进化生态学原理和SARS病毒发病传染特征 ,以有关实验结果为科学依据 ,阐述了SARS病毒的起源问题 ,指出 :我国当前环境日益严重的复合污染为SARS致病病毒的产生提供了适宜的外部生态条件和物质基础 ,SARS致病病毒可能起源于多个病毒的基因重组或融合 ,更可能是一种来自于感冒病毒进化而形成的超级感冒病毒 .可以预料 ,这一推断将为彻底解决SARS的病源提供有价值的理论指导

SARS对中国入境旅游人数影响的研究

今年爆发的SARS对中国旅游业冲击很大。本文利用双变量ARIMA模型,结合突发事件后人的心理发展变化曲线研究本次突发事件对入境旅游人数的影响。根据同类事件旅游心理恢复期的研究,结合中国实际情况,笔者讨论了恢复期分别为12、18、24个月时,SARS对入境旅游人数的影响。当恢复期为12个月时,入境旅游同比增长率平均降幅为1796%,入境旅游人数共减少238493万人次;当恢复期为18个月时,入境旅游同比增长率平均降幅为1707%,入境旅游人数共减少311703万人次;当恢复期为24个月时,入境旅游同比增长率

SARS控制与预警地理信息系统

针对我国当前非典型肺炎(SARS)疫情防治工作的迫切需求,中国科学院地理科学与资源研究所基于其在地理信息科研领域具有大型国产GIS软件平台(SuperMAP)及其在辅助决策空间信息模型工具等方面的科研优势,紧急研制了“国家SARS疫情控制与预警信息系统”。该系统由五个子系统构成,是一个将空间定位、空间信息管理、空间信息分析技术和通信技术进行有机的整合,形成了前后端一体的SARS疫情实时传输、处理、分析和分布完整的信息系统。在SARS疫情的信息采集、管理、分析及其防治与监控措施的发布等方面发挥了重要的作用。

SARS控制与预警地理信息系统的研制与应用

针对中国当前非典型肺炎(SARS)疫情防治工作的迫切需求,作者基于其在地理信息科研领域具有大型国产GIS软件平台(SuperMAP)及其在辅助决策空间信息模型工具等方面的科研优势,紧急研制了“国家SARS疫情控制与预警信息系统”。该系统由5个子系统构成,是一个将空间定位、空间信息管理、空间信息分析技术和通信技术进行有机的整合,形成了前后端一体的SARS疫情实时传输、处理、分析和分布完整的信息系统。在SARS疫情的信息采集、管理、分析及其防治与监控措施的发布等方面发挥了重要的作用。