Bibblioteca Digital de Teses e Disserta����es: uma estrat��gia de preserva����o digital

CUNHA, Jacqueline de Ara��jo. Biblioteca Digital de Teses e Disserta����es: uma estrat��gia de preserva����o da mem��ria cient��fica. 2009. 141f. Disserta����o (Mestrado)- Programa de P��s-Gradua����o em Ci��ncia da Informa����o. Universidade Federal da Para��ba, Jo��o Pessoa, 2009.

Biblioteca Digital de Teses e Disserta����es: grau de utiliza����o pelos mestrandos do curso de Ci��ncia da Informa����o das Universidades P��blicas Brasileiras

A pesquisa aborda o uso das Tecnologias de Informa����o e Comunica����o, que vem revolucionando as atividades e ocasionando muitas mudan��as relacionadas ao acesso e uso de informa����es. O objetivo foi analisar o grau de utiliza����o do conhecimento cient��fico produzido pelos Programas de P��s-Gradua����o das Universidades P��blicas Brasileiras, atrav��s da BDTD, pelos mestrandos dos referidos programas. Nos procedimentos metodol��gicos realizados, procurou-se inicialmente analisar o amplo espectro da popula����o do corpus da pesquisa. Em raz��o da impossibilidade de trabalhar com os Programas de P��s-Gradua����o como um todo, optou-se por fazer um recorte, elegendo os cursos de P��s-Gradua����o em Ci��ncia da Informa����o, vez que estes representam o principal segmento social de interesse da pesquisa. Foi utilizado o m��todo de estudo de usu��rios, onde se optou por adotar o grupo, ���estudos orientados aos usu��rios���, que identifica as necessidades e comportamento de acesso e uso da informa����o. Para coletar os dados, elaborou-se um question��rio semi-estruturado com 25 quest��es, que versavam sobre o uso, dificuldades de acesso e recupera����o da informa����o, bem como a satisfa����o na utiliza����o dessa fonte informacional. Dentre os v��rios resultados obtidos, podemos destacar o fato de que a maioria dos mestrandos (71,8%) s�� teve contato com a BDTD somente no momento em que se encontrava cursando o mestrado e, somente 24,3%, tiveram contato durante a gradua����o. Estes resultados representam um problema, que pode afetar o bom desempenho do projeto BDTD, o qual consiste em disseminar e divulgar a produ����o cient��fica dos Programas de P��s-Gradua����o das Universidades P��blicas Brasileiras para a sua comunidade. Foi observado tamb��m, que os mestrandos oriundos do curso de Biblioteconomia tende a ter contato com a BDTD bem mais cedo do que mestrandos de outros cursos de gradua����o. A fim de minimizar o problema detectado, prop��e-se uma divulga����o mais eficaz na gradua����o atrav��s de dois procedimentos: Primeiro, o docente deve fazer uma divulga����o mais eficaz da BDTD junto aos discentes de todos os cursos de gradua����o; segundo: dever�� ser feita a divulga����o na m��dia eletr��nica, atrav��s da inser����o de ��cones da BDTD, nos portais dos Departamentos dos Cursos de Gradua����o das Universidades P��blicas Brasileiras. Acredita-se que com estes procedimentos seja poss��vel aperfei��oar o uso dessa fonte de informa����o cient��fica.

Bibliotecas digitais de teses e disserta����es brasileiras: paradigma do acesso livre �� informa����o cient��fica

A evolu����o da comunica����o cient��fica ao longo do tempo e o impacto causado pela A evolu����o da comunica����o cient��fica ao longo do tempo e o impacto causado pela A evolu����o da comunica����o cient��fica ao longo do tempo e o impacto causado pela se analisar as contribui����es da Biblioteca Digital de Teses e Disserta����es (BDTD)para a comunica����o cient��fica atual, destacando possibilidades emergentes e desafios a serem superados. Apresenta uma breve evolu����o da comunica����o cient��fica ao longo do tempo; discute os impactos causados pela Internet na comunica����o, disponibiliza����o e acessibilidade de informa����es t��cnico-cient��ficas; e caracteriza BDTD destacando os desafios a serem superados. Dentre eles est��o, a quest��o dos direitos autorais que ocasionam a baixa ades��o dos autores ao projeto piloto do IBICT para disponibilizar teses e disserta����es no meio eletr��nico. Para este desafio, s��o apontadas sugest��es.

Panorama brasileiro das bibliotecas digitais de teses e disserta����es

As bibliotecas de teses e disserta����es t��m um papel fundamental para o desenvolvimento cient��fico e cultural de um pa��s. Nesse sentido, buscou-se, de modo geral, analisar o panorama brasileiro das bibliotecas digitais de teses e disserta����es. Especificamente, objetivou-se caracterizar a sociedade da informa����o enquanto contexto das BDTD; caracterizar os v��rios tipos de bibliotecas surgidos a partir da inser����o das novas tecnologias de informa����o e comunica����o; identificar as diretrizes norteadoras da implanta����o de BDTD; e levantar as BDTD existentes no Brasil. Para tato, al��m de levantamento bibliogr��fico, realizou-se uma pesquisa nos sites de institui����es de ensino superior brasileiras que j�� disp��e de bibliotecas digitais de teses e disserta����es em funcionamento. A an��lise e interpreta����o destes dados nos permite considerar que no Brasil as BDTD encontram-se num est��gio embrion��rio, sendo relevante pesquisar a hist��rica implanta����o e configura����o desse novo modelo de biblioteca.

Recorte dos produtos educacionais em hist��ria no ensino da matem��tica e em did��tica da matem��tica a partir das disserta����es e teses defendidas no brasil entre 1990-2010

This work has the main purpose of conducting a survey of educational products present in dissertations and doctoral theses focused on the use of history in mathematics teaching and Didactics of mathematics with a French foundation produced in graduate programs in the strict sense of the Brazil between 1990 and 2010, the areas of Education, Mathematics Education, school of Natural Sciences and Mathematics and related areas, according to the research proposal of Mendes (2010). Our interest was to select the products that present concrete proposals for educational activities that can be used in the classroom of Basic Education and Training of Teachers of Mathematics. The research was implemented through a bibliographic study documents the Bank of dissertations and theses from CAPES, libraries and archives of some Postgraduate programs in the country who focus their studies on the subject object of this research, besides the Brazilian Digital Library Theses and Dissertations (BDBTD). From this survey we selected works that present educational products materialized in blocks of activities based on the use of teaching history of mathematics to the classroom as well as the sequence of activities based on the Teaching of Mathematics. In possession of material, produce a CD-ROM containing the selected activities, in order to help support the work of teachers regarding the use of these activities, as a supplementary material to textbooks in their math classes

RECK-Mediated Inhibition of Glioma Migration and Invasion

Funda����o de Amparo �� Pesquisa do Estado de S��o Paulo (FAPESP)

Glioma cordoide do terceiro ventr��culo: descri����o de um novo caso

O glioma cordoide �� um tumor cerebral raro, recentemente descrito, localizado na regi��o do terceiro ventr��culo e com caracter��sticas histol��gicas, imuno-histoqu��micas e ultraestruturais peculiares. Este estudo ilustra um caso de glioma cordoide do terceiro ventr��culo em uma paciente de 59 anos de idade.

DO GLIOMA-CELLS EXPRESS CYTOKERATIN

There have been several recent reports of cytokeratin immunoreactivity in glial cells and tumors. We wanted to further test these tissues for cytokeratin immunoreactivity, and to determine whether antibody positivity corresponded to true cytokeratin expression. In the first set of experiments, a series of 10 formalin-fixed, frozen sections of glial tissue were employed; positive immunostaining with a cocktail of monoclonal anti-cytokeratin antibodies was seen only when a pepsin predigestion step was included in the immunostaining procedure. In the second set of experiments, 30 cases of malignant glioma fixed in both methacarn and formalin fixation were employed. Using a panel of three different anti-cytokeratin monoclonal antibodies (35 beta H11, 34 beta E12, CAM5.2), no positive immunostaining was observed in any of the methacarn-fixed tissues; positive immunostaining in the corresponding formalin-fixed tissue was frequently found, but only using the antibodies (35 beta H11, 34 beta E12) requiring enzyme predigestion. In the third set of experiments, immunoblots were performed on cytoskeletal extracts of human gliomas; no bands corresponding to known cytokeratins were observed in any cases. It is concluded that glial tissues and tumors do not, in fact, truly express cytokeratins, despite the fact that it is possible to obtain positive immunostaining of glial tumors and tissues using certain anti-cytokeratin antibodies under certain laboratory conditions.

Downregulation of the RECK-tumor and metastasis suppressor gene in glioma invasiveness

Invasive behavior is the pathological hallmark of malignant gliomas, being responsible for the failure of surgery, radiation, and chemotherapy. Matrix metalloproteinases (MMPs) are essential for proper ECM remodeling and invasion. The tumor and metastasis suppressor RECK protein regulates at least three members of the MMPs family: MMP-2, MMP-9, and MT1-MMP. In order to mimic the in vivo invasion process, A172 and T98G, respectively, non-invasive and invasive human glioblastoma cell lines, were cultured onto uncoated (control) or type I collagen gel-coated surface, and maintained for up to 7 days to allow establishment of the invasive process. We show that the collagen substrate causes decreased growth rates and morphological alterations correlated with the invasive phenotype. Electronic transmission microscopy of T98G cells revealed membrane invaginations resembling podosomes, which are typically found in cells in the process of crossing tissue boundaries, since they constitute sites of ECM degradation. Real time PCR revealed higher RECK mRNA expression in A172 cells, when compared to T98G cells and, also, in samples obtained from cultures where the invasive process was fully established. Interestingly, the collagen substrate increases RECK expression in A172 cells and the same tendency is displayed by T98G cells. MMPs-2 and -9 displayed higher levels of expression and activity in T98G cells, and their activities are also upregulated by collagen. Therefore, we suggest that: (1) RECK down regulation is critical for the invasiveness process displayed by T98G cells; (2) type 1 collagen could be employed to modulate RECK expression in glioblastoma cell lines. Since a positive correlation between RECK expression and patients survival has been noted in several types of tumors, our results may contribute to elucidate the complex mechanisms of malignant gliomas invasiveness.

Cloning of glucocorticoid-regulated genes in C6/ST1 rat glioma phenotypic reversion

The C6 rat glioma cell line is responsive to glucocorticoid hormones. C6 variants that are hyper-responsive (ST1) and resistant (P7) to hormone treatment have been derived previously. Glucocorticoid treatment of ST1 cells leads to complete reversion of the transformed phenotype and loss of tumorigenic potential. Production of C type retrovirus particles is also induced by glucocorticoids in ST1 cells. Cloning of the genes regulated by glucocorticoids in this cell system was used here as a strategy to uncover the gene products involved in the transformed-to-normal phenotypic change. Construction of a cDNA library from glucocorticoid-treated ST1 cells and screening by differential hybridization resulted in the isolation of three cellular sequences that code for rat metallothioneins (C27 and C41) and ��1-acid glycoprotein (C36). Northern blot analysis revealed that expression of these genes was dramatically induced by hydrocortisone in ST1 but not in P7 cells. Viral genomic RNA was used to isolate and characterize retrovirus-related sequences that could also be responsible for the phenotypic reversion phenomenon.

Pesquisa em educa����o ambiental: a atividade de campo em teses e disserta����es

P��s-gradua����o em Educa����o - IBRC

A dimens��o valorativa da educa����o ambiental na forma����o continuada de professores apresentada em teses e disserta����es brasileiras

Coordena����o de Aperfei��oamento de Pessoal de N��vel Superior (CAPES)

A ��tica ambiental na produ����o te��rica (disserta����es e teses) em educa����o ambiental no Brasil

Coordena����o de Aperfei��oamento de Pessoal de N��vel Superior (CAPES)

Os projetos de Educa����o Ambiental desenvolvidos nas escolas brasileiras: an��lise de diisserta����es e teses

P��s-gradua����o em Educa����o - IBRC

An��lise da produ����o acad��mica constante no banco de teses da Capes segundo o assunto educa����o de surdos (2005-2009)

P��s-gradua����o em Educa����o Escolar - FCLAR