Letter from Delia Jarvis Tudor to her daughter, Delia Tudor Stewart,

One letter regarding finances and news of friends, and asking her daughter when she plans to visit. One undated letter offering marital advice to Delia and discussing news regarding mutual acquaintances in South America, as well as the plans of her brother, Harry.

Miscellaneous letters addressed to Delia Tudor,

One letter, signature illegible; one letter from William C. Workman regarding a note of introduction from a Lady Percival; one letter in French from a Mr. Chauriteau in Havana.

Delia Bacon, a biographical sketch.

Includes index.

Dictionarium linguae Sinicae Latinum cum brevi interpretatione Gallica, ex radicum ordine dispositum.

Mode of access: Internet.

Cornelii Schrevelii Lexicon manuale graeco-latinum una cum vocabulario latino graeco, et collectione graecarum radicum atque gnomologia graeco-latina /

Mode of access: Internet.

Schola hebraica in qua per duas grammaticae partes, lexicon radicum, et aliquot appendices ... /

Mode of access: Internet.

Delia.

Representation of original t.-p.: Delia. Contayning certayne sonnets: With the complaint of Rosamond. Aetas prima canat veneres postrema tumultus. At London, Printed by I.C. for Simon Waterson, dwelling in Paules church-yard, at the signe of the Crowne. 1592.

Mauve: How one man invented the colour that changed the world

In an essay, "The Books of Last Things", Delia Falconer discusses the emergence of a new genre in publishing - microhistories. She cites a number of recent titles in non-fiction and fiction - Longitude, Cod, Tulips, Pushkin's Button, Nathaniel's Nutmeg, Zarafa, The Surgeon of Crowthorne, The Potato, The Perfect Storm. Delia Falconer observes of this tradition: "One has the sense, reading these books, of a surprising weight, of pleasant shock. In part, it is because we are looking at things which are generally present around us, but modestly out of sight and mind - historical nitty gritty like cod, potatoes, longitudinal clocks - which the authors have thrust suddenly, like a Biblical visitation of frogs or locusts, in our face. Things like spice and buttons and clocks are generally seen to enable history on the large scale, but are not often viewed as its worthy subjects. And by the same grand logic of history, more unusual phenomena like cabinets of curiosities or glass-making or farm lore or sailors' knots are simply odd blips on its radar screen, interesting footnotes. These new books, microhistories, reverse the usual order of history, which argues from the general to the particular, in order to prove its inevitable progress. They start from the footnotes. But by reversing the process, and walking through the back door of history, you don't necessarily end up at the front of the same house." Delia Falconer speculates about the reasons for the popularity of microhistories. She concludes: "I would like to think that reading them is not simply an exercise in nostalgia, but a challenge to the present". In Mauve, Simon Garfield provides a new way of thinking and writing about the history of intellectual property. Instead of providing a grand historical narrative of intellectual property, he tells the story of a particular invention, and its exploitation. Simon Garfield relates how English chemist William Perkin accidentally discovered a way to mass-produce colour mauve in a factory. Working on a treatment for malaria in his London home laboratory, Perkin failed to produce artificial quinine. Instead he created a dark oily sludge that turned silk a beautiful light purple. The colour was unique and became the most desirable shade in the fashion houses of Paris and London. ... The book Mauve will have a number of contemporary resonances for intellectual property lawyers and academics. Simon Garfield emphasizes the difficulties inherent in commercialising an invention and managing intellectual property. He investigates the uneasy collaboration between industry and science. Simon Garfield suggests that complaints about the efficacy of patent offices are perennial. He also highlights the problems faced by courts and law-makers in accommodating new technologies within the logic of patent law. In his elegant microhistory of the colour mauve, Simon Garfield confirms the conclusion of Brad Sherman and Lionel Bently that many aspects of modern intellectual property law can only be understood through an understanding of the past: "The image of intellectual property law that developed during the 19th century and the narrative of identity which this engendered played and continue to play an important role in the way we think about and understand intellectual property law".

New genetic loci link adipose and insulin biology to body fat distribution

Body fat distribution is a heritable trait and a well-established predictor of adverse metabolic outcomes, independent of overall adiposity. To increase our understanding of the genetic basis of body fat distribution and its molecular links to cardiometabolic traits, here we conduct genome-wide association meta-analyses of traits related to waist and hip circumferences in up to 224,459 individuals. We identify 49 loci (33 new) associated with waist-to-hip ratio adjusted for body mass index (BMI), and an additional 19 loci newly associated with related waist and hip circumference measures (P < 5 × 10−8). In total, 20 of the 49 waist-to-hip ratio adjusted for BMI loci show significant sexual dimorphism, 19 of which display a stronger effect in women. The identified loci were enriched for genes expressed in adipose tissue and for putative regulatory elements in adipocytes. Pathway analyses implicated adipogenesis, angiogenesis, transcriptional regulation and insulin resistance as processes affecting fat distribution, providing insight into potential pathophysiological mechanisms.

Clathrin-independent carriers form a high capacity endocytic sorting system at the leading edge of migrating cells

Although the importance of clathrin- and caveolin-independent endocytic pathways has recently emerged, key aspects of these routes remain unknown. Using quantitative ultrastructural approaches, we show that clathrin-independent carriers (CLICs) account for approximately three times the volume internalized by the clathrin-mediated endocytic pathway, forming the major pathway involved in uptake of fluid and bulk membrane in fibroblasts. Electron tomographic analysis of the 3D morphology of the earliest carriers shows that they are multidomain organelles that form a complex sorting station as they mature. Proteomic analysis provides direct links between CLICs, cellular adhesion turnover, and migration. Consistent with this, CLIC-mediated endocytosis of key cargo proteins, CD44 and Thy-1, is polarized at the leading edge of migrating fibroblasts, while transient ablation of CLICs impairs their ability to migrate. These studies provide the first quantitative ultrastructural analysis and molecular characterization of the major endocytic pathway in fibroblasts, a pathway that provides rapid membrane turnover at the leading edge of migrating cells.

The phylogeny and evolutionary timescale of muscoide (Diptera: Brachycera: Calyptratae) inferred from mitochondrial genomes

Muscoidea is a significant dipteran clade that includes house flies (Family Muscidae), latrine flies (F. Fannidae), dung flies (F. Scathophagidae) and root maggot flies (F. Anthomyiidae). It is comprised of approximately 7000 described species. The monophyly of the Muscoidea and the precise relationships of muscoids to the closest superfamily the Oestroidea (blow flies, flesh flies etc) are both unresolved. Until now mitochondrial (mt) genomes were available for only two of the four muscoid families precluding a thorough test of phylogenetic relationships using this data source. Here we present the first two mt genomes for the families Fanniidae (Euryomma sp.) (family Fanniidae) and Anthomyiidae (Delia platura (Meigen, 1826)). We also conducted phylogenetic analyses containing of these newly sequenced mt genomes plus 15 other species representative of dipteran diversity to address the internal relationship of Muscoidea and its systematic position. Both maximum-likelihood and Bayesian analyses suggested that Muscoidea was not a monophyletic group with the relationship: (Fanniidae + Muscidae) + ((Anthomyiidae + Scathophagidae) + (Calliphoridae + Sarcophagidae)), supported by the majority of analysed datasets. This also infers that Oestroidea was paraphyletic in the majority of analyses. Divergence time estimation suggested that the earliest split within the Calyptratae, separating (Tachinidae + Oestridae) from the remaining families, occurred in the Early Eocene. The main divergence within the paraphyletic muscoidea grade was between Fanniidae + Muscidae and the lineage ((Anthomyiidae + Scathophagidae) + (Calliphoridae + Sarcophagidae)) which occurred in the Late Eocene

Efecto de carbofuran y número de aplicaciones de chlorpyrifos sobre infestaciones de Spodoptera frugiperda (J.E. smith) (Lepidoptera: noctuidae) en maíz (Zea mays) en época de riego y primera

Con los objetivos de determinar el efecto de carbofuran y número de aplicaciones de chlorpyrifos sobre la infestación de Spodopters trugiperla (J.E. Smith), (Lepidoptera: Noctuidae) y los rendimientos en el cultivo de mal (grano), en la época de riego y de primera de 1988, se establecieron dos ensayos en el Centro Nacional de Investigaciones de Granos Básicos "San Cristobal" (Managua). Se establecieron períodos protegidos de 0-10,0-20,0-50,10-40, 20-40, 20-50, 20-30 días después de la emergencia (DDE) y testigo sin protección. Los periodos de 0-10 DDE recibieron aplicaciones de carbofuran (681 gr i.a) al suelo, los demás recibieron aplicaciones de chlorpyrtfos dirigidos al cogollo a una dosis de 0.5 1/mz. Los resultados demuestran que protección con Carbofuran durante el periodo de 0-10 DDE no hubo efecto en ambas épocas sobre las infestaciones de Spodoptera trugiperda (J.E. Smith) ni sobre el número de plantas sobrevivientes, esto indica que es un producto que no controla plagas del follaje. En época de riego, las aplicaciones de chlorpyrifos tuvieron efecto sobre el rendimiento y fueron suficientes solo 2 aplicaciones de chlorpyrifos en la segunda mitad de estadio de cogollo en forma dirigidas al cogollo, para obtener rendimientos y ganancias Iguales que las parcelas que recibieron 4 aplicaciones. En época de primera no hubo efecto de los tratamientos sobre el rendimiento debida a las bajas infestaciones de cogollero que se presentaron.

Comportamiento agronómico de 12 cultivares de tomate (Lycopersicum esculentum Mill) en condiciones de campo en Tisma, Masaya y en casa malla, en el CEVT Las Mercedes, UNA

El presente estudio se realizó en el municipio d e Tisma, Masaya y en el Centro de Experimentación y Validación de T ecnología ( CEVT ) Las Mercedes, UNA, con el objetivo de generar información sobre el comportamiento agronómico de 12 cul tivares de tomate ( Lycopersicum esculentum Mill) producidos en condiciones de campo abierto y de casa malla. El diseño experimental utilizado en Tisma fue un ensayo preliminar sin replica, en casa malla el diseño experimental utilizado fue un Látice rectangular 3x4 con dos replicas . Los datos en Tisma se analizaron a través de la obtención de medias, desviación estándar, y rendimientos relativos, en casa malla fueron evaluados a través del análisis de varianza ANDEVA y DMS u tilizado el programa SAS, 2003, V. 9.1 . Se registró la información de diez variables basada s en el comportamiento agronómico , siete cuantitativas y tres cualitativa . Los cultivares en las condiciones de casa malla mostraron diferencia significativa con respecto a las variables evaluadas, mientras que en las condiciones de campo en Tisma los cultivares presentaron diferentes medias y desviaciones estándar. Los cultivares AVTO1004 y AVTO1023 mostraron mejores re ndimientos en las condiciones de Tisma respecto al cultivar Shanty; en cambio en casa malla los cultivares Shanty, CLN3125L, AVTO 1032 , AVTO1059 , AVTO1058, AVTO1078 y AVTO10 05 presentaron los mayores rendimientos.

Prudentia Iuris, 2001, n° 54 (número completo)

Contenido: Editorial – Filosofía del Derecho: Bien común y soberanía : un viaje de ida y vuelta / Miguel Ayuso – Legalidad y bien común analizados a la luz de un caso emblemático de la experiencia jurídica italiana : entre geometría legal y dialéctica jurídica / Francesco Gentile – Las ciencias ético-sociales : división, objeto y método / Delia María Albisu – Retórica y derecho / Javier Barbieri – El concepto de Derecho y las relaciones entre Derecho Y Moral en H. L. A. Hart / Lorenzo V. Galíndez – Algunas consideraciones sobre el fundamento del Derecho / Daniel Herrera – Críticas iuspositivistas a teorías “conceptuales” de los derechos humanos / Eduardo Martín Quintana – Bien común y bien particular en el pensamiento de Santo Tomás de Aquino / Hugo Alberto Verdera – Reflexiones acerca de la justicia en Hesíodo / María de la Paz Montejano – La justicia como carácter general o índole formal propia de lo justo / Julio E. Lalanne – La concordia política en cuanto causa eficiente del Estado / Félix Adolfo Lamas – Derecho e Historia: El sufragio obligatorio en el debate de la Ley Saenz Peña / Carlos Guillermo Frontera – Algunos antecedentes históricos acerca de la motivación de sentencias / Nora Cristina González de Rosello – Los juristas argentinos y el debate en torno a la casación (1931-1943) / Ezequiel Abásolo – La cuestión romana de Pío IX / Rodolfo S. Follari – In Memoriam – Recensiones -- Documentos