998 resultados para antibiotic agent


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This paper describes a technique for the real-time modeling of deformable tissue. Specifically geared towards needle insertion simulation, the low computational requirements of the model enable highly accurate haptic feedback to a user without introducing noticeable time delay or buzzing generally associated with haptic surgery simulation. Using a spherical voxel array combined with aspects of computational geometry and agent communication and interaction principals, the model is capable of providing haptic update rates of over 1000Hz with real-time visual feedback. Iterating through over 1000 voxels per millisecond to determine collision and haptic response while making use of Vieta’s Theorem for extraneous force culling.

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Multi-agent Systems (MASs) offer strong models for representing complex and dynamic real-world environments. Taking financial investment planning as an example, this paper describes how to model complex systems from agent perspectives. Different agents and their behaviours are identified for financial investment planning. These agents are put together as an agent-based system. The experimental results show that all agents in the system can work cooperatively to provide reasonable investment advice. The system is very flexible and robust. The success of the system indicates that (MASs) can significantly facilitate the modelling of complex systems.

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Trust is a fundamental issue in multiagent systems, especially in agent-mediated e-commence. The trust model plays an important role in determining who and how to interact in open and dynamic environments. To this end, many trust models have been developed. Based on the confidence–reputation model proposed by other researchers, an improved trust model is discussed. The original model was enhanced in two aspects: (1) when evaluating the trustworthiness of target agents, the reliability of the witness itself is taken into account and further aggregated by Dempster-Shafer evidence theory and (2) the ontological property of trust is considered, which implies that trust can be calculated more precisely. A case study is provided to show the effectiveness of the improved model.

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In the present study, the influence of process control agent (PCA) on the characteristics of powder and bulk sintered Ti-16Sn-4Nb (wt. %) alloy prepared by mechanical alloying has been investigated. The elemental Ti, Sn and Nb powders were mechanically alloyed in a planetary ball mill for a short period of time using two types of PCA, namely stearic acid (SA) and ethylene bis-stearamide (EBS). The powder morphology, microstructural evolution of the bulk sintered alloy, phase formation and hardness of the alloy have been studied as a function of PCA. Results indicated that the addition of PCA leads to a delay in aIloy formation and introduces contaminations (mainly carbon and oxygen) into the material. The microstructural observation of the bulk alloy revealed a homogeneous distribution of fine Nb-rich colonies (ß-phase) within the a-Ti matrix for small amount of PCA. The hardness values of samples exhibited a significant increase with increasing amount of PCA, reaching a value of ~ 600 BV.

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Supply chain management (SCM) has received increased attention in a globally challenging environment as companies face the necessity to improve customer service and maximize profit. Therefore, dynamic reconfiguration capability is vital for supply chain management to respond to changing customer requirements and operating environments. On the other hand, for its flexible and autonomous characteristics, multi-agent systems are a viable technology for SCM, and have been widely applied in SCM. To this end, dynamic reconfiguration in agent-based SCM systems is proposed from autonomy oriented computing point of view. The performance of agent-based SCM with dynamic reconfiguration is evaluated under a modified TAC SCM scenario. With a dynamic reconfigurable SCM system, new products and processes can be introduced with considerably less expense and ramp-up time.

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Background – The olive oil phenolic, oleocanthal is a natural non-steroidal anti-inflammatory compound that irritates the oropharynx in a dose-dependent manner. It has been proposed that the biological activity of oleocanthal is partially responsible for the beneficial health effects of the Mediterranean diet. Virgin olive oil containing oleocanthal is often added as an ingredient in a number of cooked dishes and therefore it is of great importance to understand how best to preserve the putative health promoting benefits of this compound, as olive oil phenolics are
subject to heat degradation.

Objective – To investigate if oleocanthal is thermally degraded or its biological activity reduced during cooking.

Design – One extra virgin olive oil containing 54mg/kg oleocanthal was heated at varying temperatures (100°C, 170°C and 240°C) for set time periods (0, 1, 5, 20, 60, 90 min). Oleocanthal concentrations were quantified using HPLC and its biological activity determined with a taste bioassay measuring the intensity of throat irritation.

Outcomes – Results demonstrated that oleocanthal was heat stable compared with other olive oil phenolics, with a maximum loss of 16% as determined by HPLC analysis. In contrast, there was a significant decrease of up to 38% (p<0.05) in the biological activity of oleocanthal as determined by the taste bioassay.

Conclusions – Minimal degradation of oleocanthal concentration was observed upon heating however a significant decrease in the biological activity of this compound was noted with extended heating time. This has important implications for health in that, consumers may be unable to reap all of the putative health benefits associated with oleocanthal when adding virgin olive oil as an ingredient to dishes requiring prolonged heat treatment.