999 resultados para chromosome map


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Interculturality and intercultural identity is a local effect of the global movement and mixing of people, and those of intercultural identities constitute the fastest growing sector of the Australian population. In an age of globalisation and diversification, what does identity mean for those situated in-between governing notions of racial/ethnic formations, and how is intercultural identity experienced? For those informed by (at least) two cultures, what does multiculturalism, ethnicity and 'Australianness' mean, and where are these individuals positioned in relation to these structures? These questions have critical implications for the Australian nation. Within Australian discourses, interculturality and intercultural identity, in particular, has historically been excluded, rendered invisible. This dissertation is, therefore, one of facilitating visibility. Using the hyphens as a conceptual tool, I argue that in this age of accelerating globalisation the hyphens both makes visible and is made visible by interculturality. The hyphens is that grey and fluid site of intersection between structures of identity and is characterised by liminality - contestation, uncertainty, fundamentally ambivalence. Experiences of liminality, however, dissolve in any given time, opening up new terrain for creativity. Some of these emerging and creative forms of identity, as instigated by interculturality, are explored. Based on interviews with 20 daughters (and their mothers) from intercultural unions, this dissertation places intercultural identity on the Australian conceptual map and analyses the unique position occupied by those with an intercultural identity in their relationship with governing discursive formations of race/ethnicity, embodiment, nation and culture. In essence, the dissertation is concerned with examining the ways in which discursive identity structures intersect with subjective experience, and with the ways in which those with an intercultural identity negotiate those structures and their social relations. This examination raises the fundamental question: is the modernist notion of the material realities of individual lives reconcilable with the poststructural notion of identity as always located in discourse. This modernist/postmodernist tension permeates the dissertation.

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The novel explores the journey towards completion for two women and, through its concerns and structure, plays with the notion of research in the creative arts. The exegesis comments upon the concerns of the novel, and the writing and research processes.

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An investigation into choreographic processes employed within contemporary modern dance. This involved the exploration of working methods used in the making of "Deep map" nos.1, 2 & 3, presented in Melbourne from 1997-2000. The focus of that method was the placement of the dancer as 'subject' whilst maintaining the role of the choreographer as 'auteur'.

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Neural Networks have been used successfully for recognition of human gestures in many applications including analysis of motion capture data. This paper investigates the potential for using the same methods for both recognition and synthesising responses in relation to movement contained in motion capture sequences.

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In this paper, empirical results are presented which suggest that size and rate of decay of region size plays a much more significant role in the learning, and especially the development, of topographic feature maps. Using these results as a basis, a scheme for decaying region size during SOM training is proposed. The proposed technique provides near optimal training time. This scheme avoids the need for sophisticated learning gain decay schemes, and precludes the need for a priori knowledge of likely training times. This scheme also has some potential uses for continuous learning.

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In this paper, a two-stage algorithm for vector quantization is proposed based on a self-organizing map (SOM) neural network. First, a conventional self-organizing map is modified to deal with dead codebooks in the learning process and is then used to obtain the codebook distribution structure for a given set of input data. Next, subblocks are classified based on the previous structure distribution with a prior criteria. Then, the conventional LBG algorithm is applied to these sub-blocks for data classification with initial values obtained via the SOM. Finally, extensive simulations illustrate that the proposed two-stage algorithm is very effective.

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The self organising map is a well established unsupervised
learning technique which is able to form sophisticated representations of an input data set. However, conventional Self Organising Map (SOM) algorithms are limited to the production of topological maps — that is, maps where distance between points on the map have a direct relationship to the Euclidean distance between the training vectors corresponding to those points.

It would be desirable to be able to create maps which form clusters on primitive attributes other than Euclidean distance; for example, clusters based upon orientation or shape. Such maps could provide a novel approach to pattern recognition tasks by providing a new method to associate groups of data.

In this paper, it is shown that the type of map produced by SOM algorithms is a direct consequence of the lateral connection strategy employed. Given this knowledge, a technique is required to establish the feasability of using an alternative lateral connection strategy. Such a technique is presented. Using this technique, it is possible to rule out lateral connection strategies that will not produce output states useful to the organisation process. This technique is demonstrated using conventional Laplacian interconnection as well as a number of novel interconnection strategies.

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The collection contains an EBSD map of AZ31 compressed to 1% strain at room temperature in a direction parallel to the extrusion direction. The map was collected as part of an investigation into the role of twinning in the occurrence of a yield point elongation during deformation.

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Aims/hypothesis Insulin hypersecretion may be an independent predictor of progression to type 2 diabetes. Identifying genes affecting insulin hypersecretion are important in understanding disease progression. We have previously shown that diabetes-susceptible DBA/2 mice congenitally display high insulin secretion. We studied this model to map and identify the gene(s) responsible for this trait.

Methods Intravenous glucose tolerance tests followed by a genome-wide scan were performed on 171 (C57BL/6 × DBA/2) × C57BL/6 backcross mice.

Results A quantitative trait locus, designated hyperinsulin production-1 (Hip1), was mapped with a logarithm of odds score of 7.7 to a region on chromosome 13. Production of congenic mice confirmed that Hip1 influenced the insulin hypersecretion trait. By studying appropriate recombinant inbred mouse strains, the Hip1 locus was further localised to a 2 Mb interval, which contained only nine genes. Expression analysis showed that the only gene differentially expressed in islets isolated from the parental strains was Nnt, which encodes the mitochondrial proton pump, nicotinamide nucleotide transhydrogenase (NNT). We also found in five mouse strains a positive correlation (r 2  = 0.90, p < 0.01) between NNT activity and first-phase insulin secretion, emphasising the importance of this enzyme in beta cell function. Furthermore, of these five strains, only those with high NNT activity are known to exhibit severe diabetes after becoming obese.

Conclusions/interpretation Insulin hypersecretion is associated with increased Nnt expression. We suggest that NNT must play an important role in beta cell function and that its effect on the high insulin secretory capacity of the DBA/2 mouse may predispose beta cells of these mice to failure.

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Because selection is often sex-dependent, alleles can have positive effects on fitness in one sex and negative effects in the other, resulting in intralocus sexual conflict. Evolutionary theory predicts that intralocus sexual conflict can drive the evolution of sex limitation, sex-linkage, and sex chromosome differentiation. However, evidence that sex-dependent selection results in sex-linkage is limited. Here, we formally partition the contribution of Y-linked and non-Y-linked quantitative genetic variation in coloration, tail, and body size of male guppies (Poecilia reticulata)—traits previously implicated as sexually antagonistic. We show that these traits are strongly genetically correlated, both on and off the Y chromosome, but that these correlations differ in sign and magnitude between both parts of the genome. As predicted, variation in attractiveness was found to be associated with the Y-linked, rather than with the non-Y-linked component of genetic variation in male ornamentation. These findings show how the evolution of Y-linkage may be able to resolve sexual conflict. More generally, they provide unique insight into how sex-specific selection has the potential to differentially shape the genetic architecture of fitness traits across different parts of the genome.

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Kansei Engineering (KE), a technology founded in Japan initially for product design, translates human feelings into design parameters. Although various intelligent approaches to objectively model human functions and therelationships with the product design decisions have been introduced in KE systems, many or the approaches are not able to incorporate human subjective feelings and preferenees into the decision-making process. This paper proposes a new hybrid KE system that attempts to make the machine-based decision-making process closely resembles the real-world practice. The proposed approach assimilates human perceptive and associative abililities into the decision-making process of the computer. A number of techniques based on the Self-Organizing Map (SOM) neural network are employed in the backward KE system to reveal the underlying data structures that are involved in the decision-making process. A case study on interior design is presented to evaluate the efficacy of the proposed approach. The results obtained demonstrate tbe effectiveness of the proposed approach in developing an intelligent KE system which is able to combine huiiUUI feelings and preferences into its decision making process.