977 resultados para Dissemination


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This article examines the use of YouTube by the new generation of Patani 2. Muslim militants in their dissemination of propaganda and radical identity formation. These fighters have now brought their neojihadist war to the ‘Virtual’. Videos of Patani shuhada and Buddhist beheadings are regularly posted on YouTube, with the aim of legitimizing their ‘defensive jihad’. While most of the efforts in countering virtual terrorist radicalization have focused on jihadist websites, forums and blogs, very little attention has been paid to the relationship between the ‘YouTube effect’ and neojihadist violence. This article offers an analysis of the use of YouTube by the Patani Muslim insurgency in order to extract the ideological themes which enable us to understand the process of glocal neojihadist radicalization in southern Thailand.

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This paper proposes a practical and cost-effective approach to construct a fully distributed roadside communication infrastructure to facilitate the localized content dissemination to vehicles in the urban area. The proposed infrastructure is composed of distributed lightweight low-cost devices called roadside buffers (RSBs), where each RSB has the limited buffer storage and is able to transmit wirelessly the cached contents to fast-moving vehicles. To enable the distributed RSBs working toward the global optimal performance (e.g., minimal average file download delays), we propose a fully distributed algorithm to determine optimally the content replication strategy at RSBs. Specifically, we first develop a generic analytical model to evaluate the download delay of files, given the probability density of file distribution at RSBs. Then, we formulate the RSB content replication process as an optimization problem and devise a fully distributed content replication scheme accordingly to enable vehicles to recommend intelligently the desirable content files to RSBs. The proposed infrastructure is designed to optimize the global network utility, which accounts for the integrated download experience of users and the download demands of files. Using extensive simulations, we validate the effectiveness of the proposed infrastructure and show that the proposed distributed protocol can approach to the optimal performance and can significantly outperform the traditional heuristics.

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As a significant milestone in the data dissemination of wireless sensor networks (WSNs), the comb-needle (CN) model was developed to dynamically balance the sensor data pushing and pulling during hybrid data dissemination. Unfortunately, the hybrid push-pull data dissemination strategy may overload some sensor nodes and form the hotspots that consume energy significantly. This usually leads to the collapse of the network at a very early stage. In the past decade, although many energy-aware dynamic data dissemination methods have been proposed to alleviate the hotspots issue, the block characteristic of sensor nodes has been overlooked and how to offload traffic from hot blocks with low energy through long-distance hybrid dissemination remains an open problem. In this paper, we developed a block-aware data dissemination model to balance the inter-block energy and eliminate the spreading of intra-block hotspots. Through the clustering mechanism based on geography and energy, "similar" large-scale sensor nodes can be efficiently grouped into specific blocks to form the global block information (GBI). Based on GBI, the long-distance block-cross hybrid algorithms are further developed by effectively aggregating inter-block and intra-block data disseminations. Extensive experimental results demonstrate the capability and the efficiency of the proposed approach. © 2014 Elsevier Ltd.

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Although many preclinical studies have implicated β3 integrin receptors (αvβ3 and αIIbβ3) in cancer progression, β3 inhibitors have shown only modest efficacy in patients with advanced solid tumours. The limited efficacy of β3 inhibitors in patients could arise from our incomplete understanding of the precise function of β3 integrin and, consequently, inappropriate clinical application. Data from animal studies are conflicting and indicate heterogeneity with respect to the relative contributions of β3-expressing tumour and stromal cell populations in different cancers. Here we aimed to clarify the function and relative contributions to metastasis of tumour versus stromal β3 integrin in clinically relevant models of spontaneous breast cancer metastasis, with particular emphasis on bone metastasis. We show that stable down-regulation of tumour β3 integrin dramatically impairs spontaneous (but not experimental) metastasis to bone and lung without affecting primary tumour growth in the mammary gland. Unexpectedly, and in contrast to subcutaneous tumours, orthotopic tumour vascularity, growth and spontaneous metastasis were not altered in mice null for β3 integrin. Tumour β3 integrin promoted migration, protease expression and trans-endothelial migration in vitro and increased vascular dissemination in vivo, but was not necessary for bone colonization in experimental metastasis assays. We conclude that tumour, rather than stromal, β3 expression is essential and is required early for efficient spontaneous breast cancer metastasis to bone and soft tissues. Accordingly, differential gene expression analysis in cohorts of breast cancer patients showed a strong association between high β3 expression, early metastasis and shorter disease-free survival in patients with oestrogen receptor-negative tumours. We propose that β3 inhibitors may be more efficacious if used in a neoadjuvant setting, rather than after metastases are established. Copyright © 2014 Pathological Society of Great Britain and Ireland. Published by John Wiley & Sons, Ltd.

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This article verifies the importance of popular users in OSNs. The results are counter-intuitive. First, for dissemination speed, a large amount of users can swiftly distribute information to the masses, but they are not highly-connected users. Second, for dissemination scale, many powerful forwarders in OSNs cannot be identified by the degree measure. Furthermore, to control dissemination, popular users cannot capture most bridges of social communities.

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AIMS: Motivational interviewing (MI) is the most successfully disseminated evidence-based practice in the substance use disorder (SUD) treatment field. This systematic review considers two questions relevant to policymakers and service providers: (1) does training in MI achieve sustained practice change in clinicians delivering SUD treatment; and (2) do clinicians achieve a level of competence after training in MI that impacts upon client outcomes? METHODS: A systematic review was conducted and reported in line with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement, examining training outcomes for MI in the SUD treatment sector, and for clinicians working in a SUD treatment role. We determined a training method to have resulted in sustained practice change when over 75% of participants met beginning proficiency in MI spirit at a follow-up time-point. RESULTS: Of the 20 studies identified, 15 measured training at a follow-up time-point using standard fidelity measures. The proportion of clinicians who reached beginning proficiency was either reported or calculated for 11 of these studies. Only two studies met our criterion of 75% of clinicians achieving beginning proficiency in MI spirit after training. Of the 20 studies identified, two measured client substance use outcomes with mixed results. CONCLUSIONS: A broad range of training studies failed to achieve sustained practice change in MI according to our criteria. It is unlikely that 75% of clinicians can achieve beginning proficiency in MI spirit after training unless competency is benchmarked and monitored and training is ongoing. The impact of training on client outcomes requires future examination.

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Antimicrobial resistance of marine heterotrophic bacteria to different antimicrobials agents were evaluated in seawater, dry and wet sands from three marine recreational beaches with different pollution levels. In all studied beaches, the greatest frequencies of resistance were found in relation to penicillin. on Gonzaguinha, the most polluted beach, 72.3% of all isolated strains showed simple resistance, whilst 8.33% had multiple resistance. The values found on Ilha Porchat beach, were 70.8% and 6.9% for simple and multiple resistances, respectively. on GuaraA(0), the less polluted beach, only 35.3% of isolated strains had simple resistance. Multiple resistance was not observed. While samples from Gonzaguinha and Ilha Porchat beach showed isolated strains resistant to seven and six different antimicrobial agents, respectively, samples from GuaraA(0) beach were resistant only to penicillin and erytromicin. The positive correlations obtained between the degree of seawater contamination and frequency and variability of bacterial resistance indicate that polluted marine recreational waters and sands are sources of resistant bacteria contributing thus, to the dissemination of bacterial resistance.

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Poultry meat and its derivatives are among the foodstuffs considered by environmental health authorities to present the highest risks to the public. A total of 185 samples were collected in five monthly batches, from different processing stages in a sausage plant that uses mechanically-deboned chicken meat (MDCM) and tested for the presence of Salmonella. Enrichment was carried out in both Kauffman tetrathionate broth and Rappaport-Vassiliadis broth and isolation on Salmonella-Shigella agar and brilliant-green agar. Live Salmonella bacteria were isolated from six samples of the raw meat and from the emulsion, in batches three, four and five, but not from any sample in batches one or two. The six isolated strains were all classified as Salmonella Albany, which has not previously been reported in MDCM. of the two enrichment broths, Rappaport-Vassiliadis gave the better results. The Pattern of contamination suggests a probable common source, given that a new supplier was used in the third, fourth, and fifth months. It was also shown that the industrial cooking was effective in preventing Salmonella surviving in the final product.

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Prevalence and dissemination of Salmonella in a Brazilian poultry slaughterhouse were evaluated by three rapid detection systems (SS/SV(TM), VICAM, OSRT(TM), Unipath/Oxoid, and REVEAL(TM), Neogen), plus the conventional procedure. The carcasses were sampled after bleeding (P1), defeathering (P2), evisceration (P3), washing (P4), chilling (P5) and the packaged end-product (P6). In the first set of carcasses, the Salmonella incidence determined by the conventional method was 38.3% and 22.5% by SS/SV(TM). In the set for evaluation of OSRT(TM), the number of positive samples was the same detected by the cultural procedure (49.0%). In the third set, the positivity by the conventional procedure was 33.3%, and 5.0% by REVEAL(TM). The comparisons of positives in the first and third sets of carcasses were significantly different (P < 0.05). The positivity for Salmonella, in carcasses at P1 to P6, as determined by at least one of the methods, was 47.5%, 47.5%, 32.5%, 30.0%, 30.0% and 37.7%, respectively.