195 resultados para P7


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The C6 rat glioma cell line is responsive to glucocorticoid hormones. C6 variants that are hyper-responsive (ST1) and resistant (P7) to hormone treatment have been derived previously. Glucocorticoid treatment of ST1 cells leads to complete reversion of the transformed phenotype and loss of tumorigenic potential. Production of C type retrovirus particles is also induced by glucocorticoids in ST1 cells. Cloning of the genes regulated by glucocorticoids in this cell system was used here as a strategy to uncover the gene products involved in the transformed-to-normal phenotypic change. Construction of a cDNA library from glucocorticoid-treated ST1 cells and screening by differential hybridization resulted in the isolation of three cellular sequences that code for rat metallothioneins (C27 and C41) and α1-acid glycoprotein (C36). Northern blot analysis revealed that expression of these genes was dramatically induced by hydrocortisone in ST1 but not in P7 cells. Viral genomic RNA was used to isolate and characterize retrovirus-related sequences that could also be responsible for the phenotypic reversion phenomenon.

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The Archaeological Dark Earth (ADE) soils are characterized by its high fertility, dark color, and presence of pottery fragments. Regarding the formation of ADE, the most widely accepted hypothesis is that anthropogenic processes involving pre-Columbian populations made them. The purpose of this study is to characterize ADE units located in the Southern Amazon Region, in the cities of Apuí and Manicoré. Seven ADE sites were selected, trenches opened and the soil profiles characterized morphologically. Then, samples of each horizon were collected for analyses of the following physical and chemical properties: particle size, water-dispersible clay, flocculation, soil bulk density, particle density, total porosity, pH in water and KCl solutions, Ca2+, Mg2+, K+, Al3+, available P, H+Al, and organic C. Also, total oxides, free oxides and amorphous forms were analyzed. The texture of the anthropic A horizon ranged from sandy loam to clay loam. The pottery fragments and lithic material were found in similar quantities and at similar depths in the A horizons of the studied soil profiles, suggesting some similarity between the anthropogenic factors of formation. The anthropic horizons of profiles P3, P4, and P7 had a eutrophic character and high to very high levels of available phosphorus, compared to P1, P2, P5, and P6, indicating the heterogeneity of the ADEs.

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En America Latina, las tasas de mortalidad infantil han experimentado descensos que van desde un 13 por ciento a un 67 por ciento, manteniendose grandes diferencias entre paises y al interior de los paises (p7) que reflejan la desigualdad social ante la muerte, producto de la desigual distribucion de la riqueza. Los descensos logrados son mayores en las areas urbanas que en las areas rurales, de menor desarrollo y modernizacion. El examen de la mortalidad infantil segun clase social en Honduras, por ejemplo, revela que las tasas fluctuan entre 100 entre los obreros agricolas y 49 en la clase media (p23), diferencias que en distinto grado se comprueban en los demas paises de la region. Al considerar el nivel de educacion de la madre en algunos paises se constatan diferencias que fluctuan entre una tasa de mortalidad de 158 por mil entre las mujeres peruanas sin instruccion y una tasa de 44 por mil para aquellas con 7 y mas anos de instruccion; en Honduras esas cifras son de 115 y 40 por mil y en Guatemala de 106 y 36 por mil (p30).

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Pós-graduação em Agronomia (Energia na Agricultura) - FCA

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