Efeitos da obesidade e do sobrepeso sobre parâmetros cardiovasculares e respiratórios em gatos

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Estudo da remodelação cardíaca em pacientes com doença pulmonar obstrutiva crônica

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Estudo comparativo entre a lindocaína e a acupuntura no tratamento da taquicardia ventricular induzida com infusão contínua de dopamina em equinos sob anestesia geral com halotano

Pós-graduação em Medicina Veterinária - FMVZ

Variabilidade da frequência cardíaca em cães com degeneração mixomatosa crônica da valva mitral

Pós-graduação em Medicina Veterinária - FCAV

Influência da suplementação de vitamina D na remodelação ventricular após o infarto do miocárdio

Pós-graduação em Fisiopatologia em Clínica Médica - FMB

Hemodynamic and antiarrhythmic effects of lidocaine or amiodarone in dogs anesthetized with halothane

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Cardiovascular and respiratory alterations in dogs during cervical myelography using ioversol

Subarachnoid infusion of most contrast mediums and the steps involved in performing a cervical myelography have adverse affects that can discourage its use in the radiographic diagnosis of spinal cord diseases. Thus, the cardiovascular and respiratory alterations associated with neck flexion, subarachnoid puncture, and cerebrospinal fluid drainage during subarachnoid infusion of ioversol (320mgI/mL) in dogs under general anesthesia using isoflurane were evaluated. The dogs received subarachnoid infusion of autologous cerebrospinal fluid kept at 38°C - control group (GC); ioversol 0.3mL/kg at 25°C (GI25) and ioversol 0.3mL/kg heated to 38°C (GI38). Each dog had its heart rate (HR), systolic arterial pressure (SAP), diastolic arterial pressure (DAP), respiratory rate (RR), oxyhemoglobin saturation (SaO2) and electrocardiography readings (PR and QT intervals) recorded. Group comparisons showed no statistical difference regarding neck positioning, subarachnoid puncture, and subarachnoid infusion of contrast medium on HR, RR and SaO2, cardiac rhythm or conduction. However, isoflurane significantly increased PR and QT intervals. Based on these findings, it is concluded that the steps involved in cervical myelography and the use of ioversol 320mgI/mL at 0.3mL/kg (25ºC and 38ºC) during cervical myelography did not result in relevant cardiovascular and respiratory alterations, except for an elevation in arterial pressure after injection of ioversol.

Variabilidade da frequencia cardíaca em fase crônica de lesão cerebrovascular

The stroke, cause of morbidity and mortality, has been associated with imbalance in the neural control of the heart, which contributes to the decrease in heart rate variability (HRV) and a prognostic factor for cardiacevents and arrhythmias. The aim of this study was to in investigate the autonomic modulation of heart rate of men suffering from lesions stroke in chronicphase. Eight menaged 58.62 ± 2.88 years, 27.41 ± 5.33 kg/m2of bodymass índex, with paresis for at least six months were studied. Heart rate (HR) and RR intervals (iR-R) were recorded at rest in supine position for 10 minutes. Geometric índices of the Poincaré plot were calculated: SD1, associatedwith vagal activity; SD2, associated with global activity but sympathetic predominance, and the relationship of both (SD1/SD2). Geometric index values in the sample: SD1 = 20,54 ± 9,90ms; SD2 = 36,80 ± 30,61ms; SD1/SD2 = 0,49 ± 0,04. The reference values from literature for healthy subjects are: SD1 = 19.6 ± 9.4ms e 22.8 ± 16.1 ms; SD2 = 43.2 ± 17.7 ms e 56.3 ± 12.3 ms; SD1/SD2 = 0.49 ± 0.21ms. Men in chronic phase of stroke haven't autonomic dysfunction analyzed by nonlinear method – Poincaré geometricíndices.

Efeitos imediatos e a longo prazo do isolamento social de ratos adolescentes sobre a função cardiovascular

A interação social é um importante fator ambiental que pode influenciar funções fisiológicas. Estudos em humanos e animais têm demonstrado que períodos de isolamento social, principalmente em fases iniciais da vida, estão associados com alterações na função cardiovascular. Entretanto, os mecanismos relacionados com estas alterações ainda são pouco compreendidos. Estudos têm sugerido que alterações na atividade do barorreflexo pode ser um mecanismo importante relacionado com a hipertensão, além de ser um fator de risco para o desenvolvimento de arritmias e morte súbita em diversas patologias cardiovasculares. Diante disso, o objetivo do presente estudo foi investigar os efeitos imediatos e a longo prazo do isolamento social de ratos adolescentes sobre parâmetros cardiovasculares basais e a atividade do barorreflexo. O isolamento social consistiu na manutenção dos animais em caixas individuais por três semanas, do dia pós-natal 27 ao 42. Em um conjunto de animais os experimentos foram realizados imediatamente após o término do isolamento. Outro grupo de animais foi reagrupado em caixas coletivas, em grupos de quatro animais, após o término do isolamento e mantidos nesta condição por outras três semanas. Os grupos controle foram mantidos em caixas coletivas, em grupos de 4 animais, no mesmo biotério e pelo mesmo período que os animais isolados. Os animais apresentaram peso corporal reduzido após o período de isolamento social, e este efeito não foi revertido após ressocialização dos animais. O isolamento social também elevou os parâmetros basais de pressão arterial, mas este efeito foi revertido após o reagrupamento dos animais. O isolamento aumentou a resposta bradicárdica do barorreflexo desencadeada por aumento da pressão arterial... (Resumo completo, clicar acesso eletrônico abaixo)

Fatores associados com a regressão da hipertrofia esquerda em diálise e impacto com mortalidade cardiovascular

Pós-graduação em Fisiopatologia em Clínica Médica - FMB

Esplenomegalia em cães: estudo retrospectivo

The aim of this study was to review the prevalence of canine splenic disorders by means of a retrospectiveanalysis of histological diagnosis after splenectomy. The results were confronted with laboratory findings, clinical signs and presence of cardiac arrhythmia and hemoperitoneum, in an attempt to establish the differentialdiagnosis of splenomegaly. One hundred and nine dogs assisted at the Veterinary Hospital of theSchool of Veterinary Medicine and Zootechny, University of São Paulo, were included in the retrospectivestudy, between 2002 and 2009. The average age was 10 years old ± 3, with no sexual predilection. Mixedbreed dogs was the most affected kind, and average weight was 22 kg ± 13. Overall, 52% (57/109) of dogswere splenectomized due to non-neoplastic diseases and 48% (52/109) to neoplastic diseases. Among thelatter, the most common diagnosis was hemangiosarcoma (28 dogs; 54%). Most frequent clinical signs includedanorexia, lethargy and vomiting. Results showed that dogs with low red blood cell count, low hematocritvalues and/or hemoperitoneum were more likely to have splenic malignant neoplasm. On the otherhand, sex, breed, size, age, cardiac arrhythmia and other laboratory parameters were not determining factorsin the differentiation of splenomegaly.

Ritmo sinoventricular secundário a hipercalemia em gatos com obstrução uretral: breve descrição de três casos

Hyperkalemia is a common electrolyte imbalance in cats with obstructive feline lower urinary tract disease (FLUTD). The effects of serum potassium elevation in heart rhythm are serious and potentially lethal. The clinical manifestations reflect changes in the excitability of the cell membrane. Increased potassium levels lead to a reduction of the resting membrane potential of heart muscle cells, making them less excitable and resulting in cardiac arrhythmias. The sinoventricular rhythm with atrial arrest is among the types of arrhythmias caused by hyperkalemia. The purpose of this report was to highlight the importance of electrocardiographic monitoring for the early detection of potentially lethal arrhythmias in cats with obstructive FLUTD. We hereby describe the occurrence of three cases treated at the Small Animal Clinic of FMVZ/Unesp, Botucatu Campus.

Eletrocardiograma em cães: revisão

The electrocardiogram (ECG) is an important tool used in the diagnosis of cardiac arrhythmias, since it gives the graphic representation of depolarization and repolarization processes of the cardiac muscle. This study allows recording the electrical activity of myocardial cells and the underlying differences in electric potential: the magnitude of this difference is measured in millivolts (mV), and its duration is measured in seconds. The ECG is indicated when an irregular rhythm is detected during physical examination, such as bradycardias, tachycardias or arrhythmias that are not secondary to breathing, in animals with a history of syncope or weakness, for monitoring the effectiveness of antiarrhythmic therapy, in cases of putative pleural or pericardial effusion, and also in systemic diseases that lead to arrhythmia. For a reliable assessment, the ECG must be evaluated in conjunction with findings from the physical examination and clinical signs of each patient.