El papel del óxido nítrico en la modulación del proceso inflamatorio de la enfermedad periodontal

Nitric oxide (NO) is a free radical with participation in almost all physiologic host processes; however, in high concentrations it may damage the tissues. Its immunoregulatory action is present in the inflammation and in auto-immune mechanisms, being intensively studied in the medical area. Recently, some studies have also reported that NO could play a role as etiopathogenic factor of the periodontal disease, which shows inflammatory and multifactorial course. Due to beneficial or damage effects of NO, according to its concentrations, some studies have been focused in the evaluation of inhibitor of NO-Synthase (NOS) as therapeutic agents in inflammatory processes. In this context, the aim of this study was to report the role of NO and NOS inhibition in the periodontal disease modulation process. In conclusion, it could be suggested that NO seems to play an essential role in evolution of inflammatory periodontal disease, and that the NOS inhibition may be considered as a promising therapeutic in modulation of inflammatory process.

(En)quadros estéticos (artísticos e clínicos) e seus efeitos sensíveis

Based on the aesthetic investigations of Freud, the work intends to bring joints between possible sensitive effects caused by contact / reception with works of art (having them here as “framed art”) and psychoanalytic clinical setting. The text is also concerned to show that the production of these striking effects, happens by the condition of these items (artistic and clinical) are under a frame and therefore conceptualized as aesthetic in this article arguments.