Estudo sobre tratamento t��rmico e mudan��a superficial da diatomita de Puna��/RN para o desenvolvimento de um auxiliar de filtra����o

The diatomite is a natural material that has numerous applications due to changes in their physical and chemical properties after processing. It is currently used in the industry as a sound insulator , filter aid and industrial load . The filter material shall be inert chemical composition , which will diatomite confers a high commercial value and performance not found in other particulate materials , for this application. The diatomite surface undergoes changes after thermal treatment at high temperatures , from 800��C , with properties that enable its application in the food , beverage , pharmaceutical , cosmetic and textiles . In this work , we developed a study on thermal treatment on natural diatomite to adapt their properties to the application as a filter aid . The heat treatments were performed in an open oven at temperatures of 800��C , 1000��C and 1200��C for a time of 24 hours. Reagents were added in the constitution of the samples analyzed. The reagents used were sodium carbonate (Na2CO3 ) and sodium chloride (NaCl) . The samples were characterized by x - ray diffraction , x -ray fluorescence , scanning electron microscopy , analysis and particle size distribution , specific surface area by the BET method , and pore volume by BJH method. The results showed a reduction in porosity of the material as well as a significant increase in specific surface area after heat treatment and the reactants in the ratio of 3 wt%. The diatomaceous earth , after heat treatment , undergone changes in its coloration , varying in white, cream and beige , which directly interferes with the speed of filtration materials process. All results obtained before and after heat treatment of the material with the values obtained for samples already used industrially , Brazilian and American industry , which were characterized using the same test methods performed with the samples in the study were compared and showed promising efficiency when material studied in the region of Puna�� - RN , after processing , reagent addition and heat treatment, as an element in the composition of filter .

Evolu����es nas modelagens de substratos artificiais (metamateriais) com pr��ticas experimentais em antenas de microfita

Esse trabalho tem como objetivo apresentar configura����es de substratos diel��tricos inovadores projetados e fabricados a partir de estruturas metamateriais. Para isso, s��o avaliados diversos fatores que podem influenciar no seu desempenho. A princ��pio, foi feito um levantamento bibliogr��fico a respeito dos temas, que est��o relacionados com as pesquisas sobre: materiais diel��tricos, metamateriais e interferometria ��ptica. S��o estudados, pesquisados e desenvolvidos dois projetos experimentais propostos, que comprovam a efici��ncia de métodos, para se alcan��ar a permeabilidade magn��tica negativa na forma����o de metamateriais. O primeiro projeto �� a produ����o de uma nova estrutura, com u anel ressoador triangular equilateral (Split Equilateral Triangle Resonator - SETR). O segundo projeto: aplica os princ��pios da interferometria ��ptica, especialmente, com o interfer��metro de Fabry-Perot. T��cnicas para obten����o dos dispositivos que complementam a placa metamaterial como substrato foram pesquisadas na literatura e exemplificadas principalmente por meio de simula����es e medi����es. Foram feitas compara����es, simula����es e medi����es de estruturas convencionais e especiais. As experi��ncias se concentram nas evolu����es e modelagens de substratos metamateriais com aplica����es em antenas de microfita. As melhorias de alguns par��metros de desempenho de antenas tamb��m s��o relatadas. As simula����es das antenas foram feitas nos programas computacionais comerciais. Os resultados medidos foram obtidos com um analisador vetorial de redes da Rhode and Schwarz modelo ZVB 14.

Evolu����es nas modelagens de substratos artificiais (metamateriais) com pr��ticas experimentais em antenas de microfita

Esse trabalho tem como objetivo apresentar configura����es de substratos diel��tricos inovadores projetados e fabricados a partir de estruturas metamateriais. Para isso, s��o avaliados diversos fatores que podem influenciar no seu desempenho. A princ��pio, foi feito um levantamento bibliogr��fico a respeito dos temas, que est��o relacionados com as pesquisas sobre: materiais diel��tricos, metamateriais e interferometria ��ptica. S��o estudados, pesquisados e desenvolvidos dois projetos experimentais propostos, que comprovam a efici��ncia de métodos, para se alcan��ar a permeabilidade magn��tica negativa na forma����o de metamateriais. O primeiro projeto �� a produ����o de uma nova estrutura, com u anel ressoador triangular equilateral (Split Equilateral Triangle Resonator - SETR). O segundo projeto: aplica os princ��pios da interferometria ��ptica, especialmente, com o interfer��metro de Fabry-Perot. T��cnicas para obten����o dos dispositivos que complementam a placa metamaterial como substrato foram pesquisadas na literatura e exemplificadas principalmente por meio de simula����es e medi����es. Foram feitas compara����es, simula����es e medi����es de estruturas convencionais e especiais. As experi��ncias se concentram nas evolu����es e modelagens de substratos metamateriais com aplica����es em antenas de microfita. As melhorias de alguns par��metros de desempenho de antenas tamb��m s��o relatadas. As simula����es das antenas foram feitas nos programas computacionais comerciais. Os resultados medidos foram obtidos com um analisador vetorial de redes da Rhode and Schwarz modelo ZVB 14.

O fator de crescimento de fibroblasto b��sico melhora a cicatriza����o de anastomoses duodenais em ratos

RESUMO: Objetivo: Avaliar as altera����es histol��gicas, e o ganho de resist��ncia em anastomoses duodenais tratadas com fator de crescimento de fibroblasto b��sico (FGFb). Métodos: Vinte ratos da ra��a Wistar foram submetidos a sec����o transversal do duodeno, seguida de anastomose. Os animais foram divididos em 4 grupos de 5 animais cada: A1 e A2 (experimentais), nos quais foi aplicado FCFb sobre a anastomose logo ap��s seu t��rmino; e B1 e B2 (controles), nos quais foi administrada solu����o salina sobre a zona de anastomose. Os roedores foram mortos com superdose de anest��sico, sendo A1, B1 no 5�� dia e A2, B2 no 7�� dia de p��s-operat��rio. Foi feita avalia����o quanto �� resist��ncia das anastomoses �� press��o e an��lise da densidade m��dia dos achados histopatol��gicos com aux��lio do sistema digitalizado Image proPlus. Resultados: No grupo A1 a press��o suportada pelas anastomoses foi de 52��14,4 mmHg e no grupo A2 140��34,8 mmHg. Em B1 a press��o atingiu 33,6��15,2 mmHg e as anastomoses do grupo B2 suportaram press��o 105��30,3. No grupo A1 a densidade m��dia dos elementos histopatol��gicos foi de 93��9,3 e A2 atingiu 181,8��27,6. Nos grupos de controle B1 e B2 as densidades m��dias foram 67,6��16,7 e 101��12,9 respectivamente. A an��lise estat��stica revelou diferen��a significante entre nos dados dos grupos experimentais e controles (p<0,05).Conclus��o: a aplica����o t��pica do FCFb foi capaz de aumentar a resist��ncia das feridas do duodeno suturadas e observadas ap��s 5 e 7 dias de evolu����o. Estimulou a neovasculariza����o, a forma����o de fibroblastos e de fibras col��genas, melhorando os escores histol��gicos em rela����o ao controle.

An��lise fractal da vasculatura ret��nica: métodos de segmenta����o e de c��lculo dimensional

Embora tenha sido proposto que a vasculatura ret��nica apresenta estrutura fractal, nenhuma padroniza����o do m��todo de segmenta����o ou do m��todo de c��lculo das dimens��es fractais foi realizada. Este estudo objetivou determinar se a estima����o das dimens��es fractais da vasculatura ret��nica �� dependente dos métodos de segmenta����o vascular e dos métodos de c��lculo de dimens��o. Métodos: Dez imagens retinogr��ficas foram segmentadas para extrair suas ��rvores vasculares por quatro métodos computacionais (���multithreshold���, ���scale-space���, ���pixel classification��� e ���ridge based detection���). Suas dimens��es fractais de ���informa����o���, de ���massa-raio��� e ���por contagem de caixas��� foram ent��o calculadas e comparadas com as dimens��es das mesmas ��rvores vasculares, quando obtidas pela segmenta����o manual (padr��o ��ureo). Resultados: As m��dias das dimens��es fractais variaram atrav��s dos grupos de diferentes métodos de segmenta����o, de 1,39 a 1,47 para a dimens��o por contagem de caixas, de 1,47 a 1,52 para a dimens��o de informa����o e de 1,48 a 1,57 para a dimens��o de massa-raio. A utiliza����o de diferentes métodos computacionais de segmenta����o vascular, bem como de diferentes métodos de c��lculo de dimens��o, introduziu diferen��a estatisticamente significativa nos valores das dimens��es fractais das ��rvores vasculares. Conclus��o: A estima����o das dimens��es fractais da vasculatura ret��nica foi dependente tanto dos métodos de segmenta����o vascular, quanto dos métodos de c��lculo de dimens��o utilizados

Previs��o do ��ndice bovespa por meio de redes neurais artificiais: uma an��lise comparada aos métodos tradicionais de s��ries de tempo

Forecast is the basis for making strategic, tactical and operational business decisions. In financial economics, several techniques have been used to predict the behavior of assets over the past decades.Thus, there are several methods to assist in the task of time series forecasting, however, conventional modeling techniques such as statistical models and those based on theoretical mathematical models have produced unsatisfactory predictions, increasing the number of studies in more advanced methods of prediction. Among these, the Artificial Neural Networks (ANN) are a relatively new and promising method for predicting business that shows a technique that has caused much interest in the financial environment and has been used successfully in a wide variety of financial modeling systems applications, in many cases proving its superiority over the statistical models ARIMA-GARCH. In this context, this study aimed to examine whether the ANNs are a more appropriate method for predicting the behavior of Indices in Capital Markets than the traditional methods of time series analysis. For this purpose we developed an quantitative study, from financial economic indices, and developed two models of RNA-type feedfoward supervised learning, whose structures consisted of 20 data in the input layer, 90 neurons in one hidden layer and one given as the output layer (Ibovespa). These models used backpropagation, an input activation function based on the tangent sigmoid and a linear output function. Since the aim of analyzing the adherence of the Method of Artificial Neural Networks to carry out predictions of the Ibovespa, we chose to perform this analysis by comparing results between this and Time Series Predictive Model GARCH, developing a GARCH model (1.1).Once applied both methods (ANN and GARCH) we conducted the results' analysis by comparing the results of the forecast with the historical data and by studying the forecast errors by the MSE, RMSE, MAE, Standard Deviation, the Theil's U and forecasting encompassing tests. It was found that the models developed by means of ANNs had lower MSE, RMSE and MAE than the GARCH (1,1) model and Theil U test indicated that the three models have smaller errors than those of a na��ve forecast. Although the ANN based on returns have lower precision indicator values than those of ANN based on prices, the forecast encompassing test rejected the hypothesis that this model is better than that, indicating that the ANN models have a similar level of accuracy . It was concluded that for the data series studied the ANN models show a more appropriate Ibovespa forecasting than the traditional models of time series, represented by the GARCH model

An��lise de métodos para aplica����o de ventila����o natural em projetos de edifica����es em Natal-RN

Natural ventilation is an efficient bioclimatic strategy, one that provides thermal comfort, healthful and cooling to the edification. However, the disregard for quality environment, the uncertainties involved in the phenomenon and the popularization of artificial climate systems are held as an excuse for those who neglect the benefits of passive cooling. The unfamiliarity with the concept may be lessened if ventilation is observed in every step of the project, especially in the initial phase in which decisions bear a great impact in the construction process. The tools available in order to quantify the impact of projected decisions consist basically of the renovation rate calculations or computer simulations of fluids, commonly dubbed CFD, which stands for Computational Fluid Dynamics , both somewhat apart from the project s execution and unable to adapt for use in parametric studies. Thus, we chose to verify, through computer simulation, the representativeness of the results with a method of simplified air reconditioning rate calculation, as well as making it more compatible with the questions relevant to the first phases of the project s process. The case object consists of a model resulting from the recommendations of the C��digo de Obras de Natal/ RN, customized according to the NBR 15220. The study has shown the complexity in aggregating a CFD tool to the process and the need for a method capable of generating data at the compatible rate to the flow of ideas and are discarded during the project s development. At the end of our study, we discuss the necessary concessions for the realization of simulations, the applicability and the limitations of both the tools used and the method adopted, as well as the representativeness of the results obtained

An��lise de métodos de predi����o de conforto t��rmico de habita����o em clima quente-��mido com condicionamento passivo

The assessment of building thermal performance is often carried out using HVAC energy consumption data, when available, or thermal comfort variables measurements, for free-running buildings. Both types of data can be determined by monitoring or computer simulation. The assessment based on thermal comfort variables is the most complex because it depends on the determination of the thermal comfort zone. For these reasons, this master thesis explores methods of building thermal performance assessment using variables of thermal comfort simulated by DesignBuilder software. The main objective is to contribute to the development of methods to support architectural decisions during the design process, and energy and sustainable rating systems. The research method consists on selecting thermal comfort methods, modeling them in electronic sheets with output charts developed to optimize the analyses, which are used to assess the simulation results of low cost house configurations. The house models consist in a base case, which are already built, and changes in thermal transmittance, absorptance, and shading. The simulation results are assessed using each thermal comfort method, to identify the sensitivity of them. The final results show the limitations of the methods, the importance of a method that considers thermal radiance and wind speed, and the contribution of the chart proposed

Determina����o de motivos de liga����o �� quitina em vicilinas de Canavalia ensiformis e Vigna unguiculata atrav��s de métodos in silico e rela����o com suas toxicidades para o bruqu��deo Callosobruchus maculatus (Coleoptera:Bruchidae)

Chitin is an important structural component of the cellular wall of fungi and exoskeleton of many invertebrate plagues, such as insects and nematodes. In digestory systems of insects it forms a named matrix of peritrophic membrane. One of the most studied interaction models protein-carbohydrate is the model that involves chitin-binding proteins. Among the involved characterized domains already in this interaction if they detach the hevein domain (HD), from of Hevea brasiliensis (Rubber tree), the R&R consensus domain (R&R), found in cuticular proteins of insects, and the motif called in this study as conglicinin motif (CD), found in the cristallography structure of the &#946;-conglicinin bounded with GlcNac. These three chitin-binding domains had been used to determine which of them could be involved in silico in the interaction of Canavalia ensiformis and Vigna unguiculata vicilins with chitin, as well as associate these results with the WD50 of these vicilins for Callosobruchus maculatus larvae. The technique of comparative modeling was used for construction of the model 3D of the vicilin of V. unguiculata, that was not found in the data bases. Using the ClustalW program it was gotten localization of these domains in the vicilins primary structure. The domains R&R and CD had been found with bigger homology in the vicilins primary sequences and had been target of interaction studies. Through program GRAMM models of interaction ( dockings ) of the vicilins with GlcNac had been gotten. The results had shown that, through analysis in silico, HD is not part of the vicilins structures, proving the result gotten with the alignment of the primary sequences; the R&R domain, although not to have structural similarity in the vicilins, probably it has a participation in the activity of interaction of these with GlcNac; whereas the CD domain participates directly in the interaction of the vicilins with GlcNac. These results in silico show that the amino acid number, the types and the amount of binding made for the CD motif with GlcNac seem to be directly associates to the deleterious power that these vicilins show for C. maculatus larvae. This can give an initial step in the briefing of as the vicilins interact with alive chitin in and exert its toxic power for insects that possess peritrophic membrane

Estudo do genoma do v��rus causador da mionecrose infecciosa em camar��es e desenvolvimento de métodos para detec����o de diferentes variantes

Shrimp farming is one of the activities that contribute most to the growth of global aquaculture. However, this business has undergone significant economic losses due to the onset of viral diseases such as Infectious Myonecrosis (IMN). The IMN is already widespread throughout Northeastern Brazil and affects other countries such as Indonesia, Thailand and China. The main symptom of disease is myonecrosis, which consists of necrosis of striated muscles of the abdomen and cephalothorax of shrimp. The IMN is caused by infectious myonecrosis virus (IMNV), a non-enveloped virus which has protrusions along its capsid. The viral genome consists of a single molecule of double-stranded RNA and has two Open Reading Frames (ORFs). The ORF1 encodes the major capsid protein (MCP) and a potential RNA binding protein (RBP). ORF2 encodes a probable RNA-dependent RNA polymerase (RdRp) and classifies IMNV in Totiviridae family. Thus, the objective of this research was study the IMNV complete genome and encoded proteins in order to develop a system differentiate virus isolates based on polymorphisms presence. The phylogenetic relationship among some totivirus was investigated and showed a new group to IMNV within Totiviridae family. Two new genomes were sequenced, analyzed and compared to two other genomes already deposited in GenBank. The new genomes were more similar to each other than those already described. Conserved and variable regions of the genome were identified through similarity graphs and alignments using the four IMNV sequences. This analyze allowed mapping of polymorphic sites and revealed that the most variable region of the genome is in the first half of ORF1, which coincides with the regions that possibly encode the viral protrusion, while the most stable regions of the genome were found in conserved domains of proteins that interact with RNA. Moreover, secondary structures were predicted for all proteins using various softwares and protein structural models were calculated using threading and ab initio modeling approaches. From these analyses was possible to observe that the IMNV proteins have motifs and shapes similar to proteins of other totiviruses and new possible protein functions have been proposed. The genome and proteins study was essential for development of a PCR-based detection system able to discriminate the four IMNV isolates based on the presence of polymorphic sites

Remo����o de metais pesados em efluentes sint��ticos utilizando vermiculita como adsorvente

Heavy metals are used in many industrial processestheirs discard can harm fel effects to the environment, becoming a serious problem. Many methods used for wastewater treatment have been reported in the literature, but many of them have high cost and low efficiency. The adsorption process has been used as effective for the metal remoal ions. This paper presents studies to evaluate the adsorption capacity of vermiculite as adsorbent for the heavy metals removal in a synthetic solution. The mineral vermiculite was characterized by differents techniques: specific surface area analysis by BET method, X-ray diffraction, raiosX fluorescence, spectroscopy in the infraredd region of, laser particle size analysis and specific gravity. The physical characteristics of the material presented was appropriate for the study of adsorption. The adsorption experiments weredriveal finite bath metod in synthetic solutions of copper, nickel, cadmium, lead and zinc. The results showed that the vermiculite has a high potential for adsorption, removing about 100% of ions and with removal capacity values about 85 ppm of metal in solution, 8.09 mg / g for cadmium, 8.39 mg/g for copper, 8.40 mg/g for lead, 8.26 mg/g for zinc and 8.38 mg/g of nickel. The experimental data fit in the Langmuir and Freundlich models. The kinetic datas showed a good correlation with the pseudo-second order model. It was conducteas a competition study among the metals using vermiculiti a adsorbent. Results showed that the presence of various metals in solution does not influence their removal at low concentrations, removing approximat wasely 100 % of all metals present in solutions

Simula����o do escoamento monof��sico em um est��gio de uma bomba centr��fuga utilizando t��cnicas de fluidodin��mica computacional

Oil production and exploration techniques have evolved in the last decades in order to increase fluid flows and optimize how the required equipment are used. The base functioning of Electric Submersible Pumping (ESP) lift method is the use of an electric downhole motor to move a centrifugal pump and transport the fluids to the surface. The Electric Submersible Pumping is an option that has been gaining ground among the methods of Artificial Lift due to the ability to handle a large flow of liquid in onshore and offshore environments. The performance of a well equipped with ESP systems is intrinsically related to the centrifugal pump operation. It is the pump that has the function to turn the motor power into Head. In this present work, a computer model to analyze the three-dimensional flow in a centrifugal pump used in Electric Submersible Pumping has been developed. Through the commercial program, ANSYS�� CFX��, initially using water as fluid flow, the geometry and simulation parameters have been defined in order to obtain an approximation of what occurs inside the channels of the impeller and diffuser pump in terms of flow. Three different geometry conditions were initially tested to determine which is most suitable to solving the problem. After choosing the most appropriate geometry, three mesh conditions were analyzed and the obtained values were compared to the experimental characteristic curve of Head provided by the manufacturer. The results have approached the experimental curve, the simulation time and the model convergence were satisfactory if it is considered that the studied problem involves numerical analysis. After the tests with water, oil was used in the simulations. The results were compared to a methodology used in the petroleum industry to correct viscosity. In general, for models with water and oil, the results with single-phase fluids were coherent with the experimental curves and, through three-dimensional computer models, they are a preliminary evaluation for the analysis of the two-phase flow inside the channels of centrifugal pump used in ESP systems

&#65279;Potencial larvicida��de extratos de plantas regionais no controle de larvas de��Aedes��aegypti

&#65279;Dengue, amongst the virus illnesses one can get by vectorial transmission, is the one that causes more impact in the morbidity and mortality of world s population. The resistance to the insecticides has caused difficulties to control of vector insect (Aedes aegypti) and has stimulated a search for vegetables with larvicidal activity. The biodiversity of Caatinga is barely known and it is potential of use even less. Some plants of this biome are commercialized in free fairs northeast of Brazil, because of its phytotherapics properties. The vegetables in this study had been selected by means of a questionnaire applied between grass salesmen and natives of the Serido region from Rio Grande do Norte state; culicids eggs had been acquired with traps and placed in container with water for the larva birth. Thirty larvae had been used in each group (a group control and five experimental groups), with four repetitions four times. The vegetables had been submitted to the processes of decoction, infusion and maceration in the standard concentration of 100g of the vegetable of study in 1l of H2O and analyzed after ��, 1, 2, 4, 8, 12, 24 and 48 hours for verification of the average lethal dose (LD50) from the groups with thirty larva. The LD50 was analyzed in different concentrations (50g/l, 100g/l, 150g/l, 200g/l e 300g/l) of Aspidosperma pyrifolium Mart. 48 extracts of rind, leaf and stem of the seven vegetal species: Aspidosperma pyrifolium Mart., Mimosa verrucosa Benth, Mimosa hostilis (Mart.) &#65279;Benth., Myracrodruon urundeuva Allem��o, Ximenia americana L, Bumelia sartorum Mart Zizyphus joazeiro Mart, had been analyzed. The extracts proceeding from the three methods were submitted to the freezedrying, to evaluate and to quantify substances extracted in each process. The results had shown that Aspidosperma pyrifolium Mart. and Myracrodruon urundeuva Allem��o are the species that are more distinguished as larvicidal after 24 hours of experiment, in all used processes of extraction in the assays. The Zizyphus joazeiro Mart species has not shown larvicidal activity in none of the assays. In relation to the extraction method, the decoction was the most efficient method in the mortality tax of the A. aegypti larvae

Efeito antiinflamat��rio de fucana extra��da da alga Parda spatoglossum schroederii em modelos experimentais de Peritonite, choque n��o s��ptico e colite

Fucans is a name used for sulfated polysaccharides, which is most characteristic structure of the presence of sulfated L-fucose, are found in brown seaweed (Phaeophyceae) and echinoderms (sea urchins and sea cucumbers). These polysaccharides have been reported to possess anticoagulant, antitumor, anti-viral, anti-proliferative and anti-inflammatory activities. Therefore, in the present study was evaluate the effect of the fucan from the brown seaweed Spatoglossum schroederii in models of peritonitis and non-septic shock induced by zymosan, as well as in a murine model of colitis induces by DSS. So, the mice treatment by intravenous route with the fucan was able to reduce the exudate formation and the cell migration in the model of acute peritonitis induced by zymosan during the kinetic of 6, 24 and 48 hours. Similarly, in the model of non-septic shock induced by zymosan the fucan demonstrated a protector effect to inhibited the cellular migration to the peritoneo, to decrease the levels of IL-6 in the serum and in the peritoneal exudate, to attenuate the lose of weight in the mice; beside to reduce the serum levels of hepatic transaminases and as well as the liver injury. In the model of murine colitis, the treatment with the fucan reduced the lose of weight of the animals, decreased the levels of IL-17 and IFN-&#61543; produced in the gut and decrease the intestinal lesion induced by DSS. In conclusion, the fucan used in this study presented a significant protector effect in the murine models of inflammation

Avalia����o de efeitos biol��gicos de antiinflamat��rios derivados do ��cido propi��nico atrav��s de modelos experimentais em n��vel molecular e celular

Derivatives of propionic acid NSAIDs are irreversible inhibitors of cyclooxygenase enzyme widely used. The aim of this study was to evaluate, through different experimental models, biological effects of derivatives of propionic acid (fenoprofen, naproxen, ibuprofen and ketoprofen) in cellular and molecular level. The labeling of blood constituents with technetium-99m (99mTc) and morphological analysis of erythrocytes of blood of rats, as well as growth, survival of cultures of Escherichia coli (E. coli) and the assessment of bacterial plasmid electrophoretic profiles were models used for experimental evaluation of possible biological effects of antiinflammatory drugs. The results show that, in general, anti-inflammatory drugs evaluated were not able to alter the labeling of blood constituents with 99mTc, the morphology of red blood cells from blood of rats, as well as the growth of cultures of E. coli and the electrophoretic profile of plasmid DNA. However, naproxen appears to cytotoxic effect on bacterial cultures, plasmids and genotoxic effects in reducing the action of stannous chloride in cultures of E. coli. The use of experimental fast performance and low cost was important for assessment of biological effects, contributing to a better understanding of the properties of propionic acid derivatives studied. anti-inflammatory, blood constituents, technetium-99m, stannous chloride, Escherichia coli; DNA