Corpo, doença e biomedicina: uma análise antropológica de práticas corporais e de tratamento entre pessoas com HIV/AIDS

A epidemia do HIV/AIDS tem desafiado tanto a biomedicina como a ciência de modo geral. Tecnologias vêm sendo exploradas a fim de criar uma base terapêutica consistente às pessoas infectadas. Se os tratamentos exigem o consumo diário de medicamentos, os exames laboratoriais contemplam uma rotina a ser sempre mantida. Levam a um processo de mudança e adaptação pessoal junto de uma reorganização intensiva das formas de cuidado do corpo. As práticas clínico-terapêuticas devem ser entendidas, porém, como elementos particulares de processos culturais de grande alcance. Partindo de pesquisa etnográfica no Rio de Janeiro, discuto os efeitos sociais da biomedicina como um saber e uma cultura global sobre práticas sociais locais.

Doença, ativismo biossocial e cidadania terapêutica: a emergência da mobilização de pessoas com HTLV no Brasil

O artigo aborda a emergência da mobilização social e política de pessoas infectadas pelo HTLV, na década de 2000. Com fortes vínculos com o ativismo de HIV/Aids, pessoas com HTLV e seus grupos e organizações engendraram práticas sociais, discursos e identidades que contribuem para se pensar em termos teóricos e históricos sobre a questão das biossocialidades e da cidadania terapêutica

Análise da estrutura genética populacional da piraúna (cephalopholis fulva: serranidae) ao longo da costa e ilhas oceânicas brasileiras

Brazil has about 8,500 km of coastline and on this scale, fishing is a historically important source of animal protein for human consumption. The national fishing background shows a growth of marine fishery production until 1985 and within this period it was recorded a steady decline. From the year 2003 fishing statistics aim to some "recovery" of the total fisheries production, which probably is related to a change in industry practice. The target of commercial fishing became smaller species with low commercial value, but very abundants. The coney, Cephalopholis fulva (Serranidae), is one of these species that have been suffering a greater fishing pressure in recent years. In order to provide data about the current situation of the genetic diversity of these populations, several molecular markers have been being used for this purpose. The prior knowledge of genetic variability is crucial for management and biodiversity conservation. To this end, the control region sequences (dloop) of mtDNA from Cephalopholis fulva (Serranidae) from five geographical points of the coast of Brazil (Ceará, Rio Grande do Norte, Bahia and Espírito Santo) and the Archipelago of Fernando de Noronha (FN) were sequenced and their genetic diversity analyzed. The FST values were very low (0.0246 to 0.000), indicating high gene flow between the sampled spots. The indices h and indicate a secondary contact between previously allopatric lineages differentiated or large and stable populations with long evolutionary history. Tests of Tajima and Fu showed expansion for all populations. In contrast, the mismatch distribution and SSD indicated expansion just for coastal populations. Unlike other species of the Atlantic which have been deeply affected by events on later Pleistocene, the population-genetic patterns of C. fulva may be related to recent events occurred approximately 130,000 years ago. Moreover, the data presented by geographical samples of the specie C. fulva showed high genetic diversity, also indicating the absence of deleterious effects of over-exploitation on this specie, as well as evidence of complete panmixia between all sampled populations

Análise imuno-histoquímica de proteínas relacionadas às respostas Th1, Th2 e Th17 na doença periodontal

Periodontal disease is an inflammatory condition of infectious nature characterized by destruction of protecting and supporting dental tissues. It happens as a response produced by the host when attacked by microorganisms. Several factors are involved in this process. Among them, cytokines are key regulatory molecules in this immune response, playing a role either protective and/or destructive in lesion progression. Thus, this study investigated the immunohistochemical expression of IFN- , GATA-3, IL-17, IL-23, IL-6 and TGF- in gingival tissues of humans, in an attempt to gain a better understanding of the participation of Th1, Th2 and Th17 immune responses in the development of periodontal disease processes. To this end, eighty-two samples of gingival tissues were divided into three groups: Group 1 = 15 (samples of healthy gum tissue as controls), Group 2 = 36 (samples with chronic gingivitis) and Group 3 = 31 (samples with chronic periodontitis). All cases were submitted to morphological analysis from sections stained with hematoxylin and eosin and then subjected to staining by immunohistochemistry using the streptavidin-biotin method. Results showed positive labeling for all proteins. Nonetheless, we observed a greater expression of Th1 cytokines and Th17 cells in group 3. We found statistically significant difference between TGF- expression and the clinical condition of the samples (p=0.02). We conclude that Th1 and Th17 responses may act synergistically in the destructive process of periodontal tissue, overlapping the Th2 response that was also present in these tissues

Organização espacial e processo saúde-doença no bairro Guarapes, Natal/RN

La santé et la maladie sont des objets de préoccupation dans la société. Tout au long de l'histoire de l'humanité, ils ont été traités sous différents yeux. La géographie est une façon de comprendre les processus liés à des questions de santé et de maladie, de façon privilégiée dans le but d'être une science concernées par la zone géographique où cela implique non seulement une structure de la matière, mais les personnes et les flux découlant de la relation est établie Entre la société et la nature. Un lien est établi entre l'organisation spatiale de la santé-maladie est au c ur de ce travail, avec la coupe Guarapes espace du quartier, situé dans l'ouest de la Région administrative de Natal (plus bolsão pauvreté de la ville) pour la période correspondante de la 1990 par 2004 (jalon important pour le bien et la dynamique des populations de la zone d'étude) et de réduire le temps de la recherche. Au cours de l'analyse procède à l'étude des formes de production et d'organisation de l'espace vécu. Depuis comprendre le quotidien des personnes souffrant d'un réseau de relations, motivés par les besoins et la solidarité qui génèrent des formes et des contenus qui façonnent l'aire géographique. Sur la base de revue de la littérature, la recherche empirique à travers la réalisation des feuilles de route des entretiens avec le représentant des gens du quartier (résidents, des dirigeants communautaires, des coordonnateurs pédagogiques, des infirmières et des agents de santé de la PSF). Outre les visites effectuées à l'Agence de régulation des services d'assainissement de la municipalité de Noël - ARSBAN, le Secrétariat spécial pour l'Environnement et Urbanisme - SEMURB, secrétaire du Travail et de la protection sociale SEMTAS, Secrétariat municipal de la santé - SMS. Sur la base de l'espace vécu voir que les éléments du quotidien local exercer une forte influence sur la santé et La maladie de la population étudiée, avec un accent sur les problèmes découlant de chômage, sous-emploi, l'insécurité et un manque d'assiduité de certains responsables de l'USF - Guarapes. La production et l'organisation de la région convergent à l'apparition de maisons, les rues et les petits commerces non équipés de l'infrastructure de base dédiée à la prise en charge des personnes favorables à l'occupation désordonnée et non planifiée pour plusieurs zones du district, ainsi que l'apparition De vecteurs transmetteurs de maladies