Current developments and future challenges for the creation of aortic heart valve

The concept of tissue-engineered heart valves offers an alternative to current heart valve replacements that is capable of addressing shortcomings such as life-long administration of anticoagulants, inadequate durability, and inability to grow. Since tissue engineering is a multifaceted area, studies conducted have focused on different aspects such as hemodynamics, cellular interactions and mechanisms, scaffold designs, and mechanical characteristics in the form of both in vitro and in vivo investigations. This review concentrates on the advancements of scaffold materials and manufacturing processes, and on cell–scaffold interactions. Aside from the commonly used materials, polyglycolic acid and polylactic acid, novel polymers such as hydrogels and trimethylene carbonate-based polymers are being developed to simulate the natural mechanical characteristics of heart valves. Electrospinning has been examined as a new manufacturing technique that has the potential to facilitate tissue formation via increased surface area. The type of cells utilized for seeding onto the scaffolds is another factor to take into consideration; currently, stem cells are of great interest because of their potential to differentiate into various types of cells. Although extensive studies have been conducted, the creation of a fully functional heart valve that is clinically applicable still requires further investigation due to the complexity and intricacies of the heart valve.

Structures, processes and performance of corporate and business ethics in supply chains

The objective of this paper is to introduce and describe a conceptual framework of firms' corporate and business ethics in supply chains in terms of ethical structures, ethical processes and ethical performance. A framework is outlined and positioned incorporating an ethical frame of reference in the field of Supply Chain Management (SCM). A number of areas and sub-areas of firms' corporate and business ethics are framed in the context of supply chains. The introduced framework should be seen as a seed for further development and refinement in the field of SCM. It provides opportunities for further research of ethical concerns in supply chains.

Role of internal cognitive processes and external causal attributions in midlife transition

This project was designed to ascertain the defining attributes of midlife that render it distinct from young and older adulthood. Based on the determined salient factors the Midlife Adjustment Scale was developed and the nature of midlife, that of a transitional period, was established. The scale was then used to assess the influence that perceived control and major life events have on one's adjustment during the middle years.

The outcomes, processes, and challenges of inclusive education in Victoria

A collaborative school culture is important to improve the learning of students with special education needs. This could be met through a consolidation of a school's understanding of students' learning difficulties as environmental causes and an increase of teachers' confidence and knowledge on addressing students' diverse needs.

Criminal processes and investigative procedures : Victoria and Commonwealth

This book is designed to be a useful and practical tool for both students and legal practitioners alike. In addition to focusing on the recently enacted Criminal Protective Act 2009, this text also highlights other key aspects of the criminal processes.

Heterogeneous electrode processes and localized corrosion

This book covers the areas of electrochemical heterogeneity and electrode inhomogeneity and their effects on nonuniform electrode processes, in particular, localized corrosion. It covers the fundamentals, experimental methods, and engineering aspects of electrochemical heterogeneity.

Effect of manufacturing method and aging environment on painted automotive carbon fibre composite surfaces

In this paper, the effect of various aging environments on the painted surface finish of unidirectional carbon fibre composite laminates, manufactured by autoclave and a novel out-of-autoclave technique was investigated. Laminates were exposed to water immersion, 95 % relative humidity and cyclic environments for 552 h and the surface finish was evaluated using visual and wave-scan distinctness of image (DOI) techniques. It was found that the laminate surface finish was dependent on the amount of moisture in the aging test. Minor surface waviness occurred on the laminates exposed to the cyclic test, whereas, surface waviness, print through and DOI values were all significantly higher as the laminates absorbed larger quantities of moisture from the hygrothermal and hydrothermal tests. The water immersion test, which was the most detrimental to the surface finish of the painted laminates, produced dense blistering on the autoclave manufactured laminate surface whereas the out-of-autoclave laminate surface produced only a few. It was found that the out-of-autoclave laminate had high substrate surface roughness which resulted in improved paint adhesion and, therefore, prevented the formation of surface blistering with aging. © 2012 Springer Science+Business Media Dordrecht.

Urban informality in the developing world - Opportunistic urban design processes and prototypes for the developed world

The turn of the twenty first century heralds a fundamental shift in the world’s population towards cities in what has been termed The Urban Age, most visible in the developing world. Instead of the dichotomy of ‘First World models’ and ‘Third world problems’, research has begun to explore the complexities of urban informality revealing new approaches to the complex creation of urban spaces. This paper will analyse the prevailing perspectives in order to develop an understanding of informality as an urban evolution through necessity. Finally through an analysis of professional urban design experiments the paper highlights opportunities and challenges within the developing world for new and exciting urban design processes in the developed world.

Implementation of six sigma in Australian manufacturing small and medium enterprises

The present study discusses the status of quality management practices in manufacturing SMEs in Australia and investigates the reasons why they are not implementing the Six Sigma methodology. This study emphasises that Six Sigma can be implemented in manufacturing SMEs. Moreover, this study identifies the motivation for adopting Six Sigma by Australian manufacturing SMEs. A Six Sigma implementation framework is developed and presented.

Analysis of psycholinguistic processes and topics in online autism communities

Current growth of individuals on the autism spectrum disorder (ASD) requires continuous support and care. With the popularity of social media, online communities of people affected by ASD emerge. This paper presents an analysis of these online communities through understanding aspects that differentiate such communities. In this paper, the aspects given are not expressed in terms of friendship, exchange of information, social support or recreation, but rather with regard to the topics and linguistic styles that people express in their on-line writing. Using data collected unobtrusively from LiveJournal, we analyze posts made by ten autism communities in conjunction with those made by a control group of standard communities. Significant differences have been found between autism and control communities when characterized by latent topics of discussion and psycholinguistic features. Latent topics are found to have greater predictive power than linguistic features when classifying blog posts as either autism or control community. This study suggests that data mining of online blogs has the potential to detect clinically meaningful data. It opens the door to possibilities including sentinel risk surveillance and harnessing the power in diverse large datasets.