Developmental stress can uncouple relationships between physiology and behaviour

Phenotypic correlations (rP) have frequently been observed between physiological and behavioural traits, and the nature of these associations has been shown to be modulated by a range of environmental stressors. Studies to date have examined the effects of acute stressors on physiology-behaviour interrelations, but the potential for permanent changes induced by exposure to stress during development remains unexplored. We exposed female zebra finches to dietary restriction during the nestling stage and tested how this affected rP among a variety of physiological traits (haematocrit, stress-induced corticosterone level and basal metabolic rate (BMR)) and behavioural traits (activity and feeding rates in novel and familiar environments). Developmental stress completely uncoupled the relationship between activity in a novel environment and two physiological traits: haematocrit and BMR. This suggests that nutritionally based developmental stress has provoked changes in the energy budget that alleviate the trade-off between maintenance (BMR) and locomotor activities.

Early-developmental stress, repeatability, and canalization in a suite of physiological and behavioral traits in female zebra finches

Adaptive developmental plasticity allows individuals experiencing poor environmental conditions in early life to adjust their life-history strategy in order to prioritize short-term fitness benefits and maximize reproductive output in challenging environments. Much research has been conducted to test whether such adoption of a "faster" life-history strategy is accompanied by concordant changes in behavior and physiology, with mixed results. As research in this field has focused on comparison of mean-level responses of treatment groups, few studies include repeated measures of response variables and the effect that developmental stress may have on repeatability per se. We investigated how early-developmental stress affects the mean expression of (and repeatability in) a variety of behavioral and physiological traits in female zebra finches. We predicted that: (1) individuals subjected to nutritional restriction in the nestling phase would have higher feeding and activity rates, with associated increases in hematocrit and basal metabolic rates (BMRs), (2) nutritional restriction in early life would alter adults' stress-induced corticosterone level, and (3) developmental stress would, respectively, influence the amount of among-individual and within-individual variation in behavioral and physiological traits, hence affecting the repeatability of these traits. In comparison to control females, stressed females did not differ in activity rate or stress-induced corticosterone level, but they did have higher levels of feeding, hematocrit, and BMR. Among-individual variance and repeatability were generally higher in stressed females than in controls. Finally, we found that developmental dietary restriction significantly reduced the amount of within-individual variance both in activity rate in the novel environment and in stress-induced corticosterone level. Our results not only confirm previous findings on the effect of early-developmental stress on BMR, but also extend its effect to feeding rate and hematocrit, suggesting that developmental plasticity in these traits is ontogenetically linked. Early-developmental stress may disable particular genetic canalizing processes, which would release cryptic genetic variation and explain why repeatability and among-individual variance were generally higher in the stressed groups than in controls. For activity rate in the novel environment and with stress-induced corticosterone level, however, early-developmental stress significantly reduced within-individual variance, which may be a consequence of increased canalization of these traits at the micro-environmental level.

An investigation of the developmental assumptions underlying age-based legal criteria in the Children’s Court.

This thesis investigated developmental trends in the psychological abilities presumed to underpin the doli incapax presumption in Victoria, Australia. Findings from this study questioned the utility of the doli incapax presumption as it currently stands, and highlighted the need for a purpose-built interview protocol when assessing young people's culpability.

Analysis of backward congestion notification with delay for enhanced Ethernet networks

At present, companies and standards organizations are enhancing Ethernet as the unified switch fabric for all of the TCP/IP traffic, the storage traffic and the high performance computing traffic in data centers. Backward congestion notification (BCN) is the basic mechanism for the end-to-end congestion management enhancement of Ethernet. To fulfill the special requirements of the unified switch fabric, i.e., losslessness and low transmission delay, BCN should hold the buffer occupancy around a target point tightly. Thus, the stability of the control loop and the buffer size are critical to BCN. Currently, the impacts of delay on the performance of BCN are unidentified. When the speed of Ethernet increases to 40 Gbps or 100 Gbps in the near future, the number of on-the-fly packets becomes the same order with the buffer size of switch. Accordingly, the impacts of delay will become significant. In this paper, we analyze BCN, paying special attention on the delay. We model the BCN system with a set of segmented delayed differential equations, and then deduce sufficient condition for the uniformly asymptotic stability of BCN. Subsequently, the bounds of buffer occupancy are estimated, which provides direct guidelines on setting buffer size. Finally, numerical analysis and experiments on the NetFPGA platform verify our theoretical analysis.

Reduced order functional observers with application to partial state estimation of linear systems with input delay

Reduced order multi-functional observer design for multi-input multi-utput (MIMO) linear time-invariant (LTI) systems with constant delayed inputs is studied. This research is useful in the input estimation of LTI systems with actuator delay, as well as system monitoring and fault detection of these systems. Two approaches for designing an asymptotically stable functional observer for the system are proposed: delay-dependent and delay-free. The delay-dependent observer is infinite-dimensional, while the delay-free structure is finite-dimensional. Moreover, since the delay-free observer does not require any information on the time delay, it is more practical in real applications. However, the delay-dependent observer contains less restrictive assumptions and covers more variety of systems. The proposed observer design schemes are novel, simple to implement, and have improved numerical features compared to some of the other available approaches to design (unknown-input) functional observers. In addition, the proposed observers usually possess lower order than ordinary Luenberger observers, and the design schemes do not need the observability or detectability requirements of the system. The necessary and sufficient conditions of the existence of an asymptoticobserver in each scenario are explored. The extensions of the proposed observers to systems with multiple delayed-inputs are also discussed. Several numerical examples and simulation results are employed to support our theories.

New generalized Halanay inequalities with applications to stability of nonlinear non-autonomous time-delay systems

In this paper, a general class of Halanay-type non-autonomous functional differential inequalities is considered. A new concept of stability, namely global generalized exponential stability, is proposed. We first prove some new generalizations of the Halanay inequality. We then derive explicit criteria for global generalized exponential stability of nonlinear non-autonomous time-delay systems based on our new generalized Halanay inequalities. Numerical examples and simulations are provided to illustrate the effectiveness of the obtained results.

Neoliberalism, the developmental state and civil society in Korea

Following the Asian economic crisis of the late 1990s, some scholars predicted that the introduction of neoliberal ideas and policies would result in the definitive passing of the Korean developmental state. Despite these predictions, Korean state elites have retained their influential position as economic managers by, for instance, practicing a revised form of industrial policy. Neoliberal reform has, however, had significant social implications. Rather than neoliberalism acting as a democratising force that curtails the power of the state, this article illustrates that the Korean state has used the reform agenda to justify an expansion of its powers. The state presented itself as an agent capable of resolving long-standing economic problems, and of defending law and order. By doing so, the state reduced the political space available to non-state actors. The article concludes that for some states, neoliberalism is a means of retaining economic and political influence, and that former developmental states may be particularly adept at co-opting elements of civil society into governing alliances.

Linear functional state bounding for perturbed time-delay systems and its application

This paper considers time-delay systems with bounded disturbances. We study a new problem of finding an upper bound of an absolute value function of any given linear functional of the state vector starting from the origin of the system. Based on the Lyapunov-Krasovskii method combining with the recent Wirtinger-based integral inequality that has just been proposed by Seuret & Gouaisbaut (2013. Wirtinger-based integral inequality: application to time-delay systems. Automatica, 49, 2860-2866), sufficient conditions for the existence of an upper bound of the function are derived. The obtained results are shown to be more effective than those adapted from the existing works on reachable set bounding. Furthermore, the obtained results are applied to refine existing ellipsoidal bounds of the reachable sets. The effectiveness of the obtained results is illustrated by two numerical examples.

Developmental improvements in reaching correction efficiency are associated with an increased ability to represent action mentally

We investigated the purported association between developmental changes in the efficiency of online reaching corrections and improved action representation. Younger children (6-7years), older children (8-12years), adolescents (13-17years), and young adults (18-24years) completed a double-step reaching paradigm and a motor imagery task. Results showed similar nonlinear performance improvements across both tasks, typified by substantial changes in efficiency after 6 or 7years followed by incremental improvements. Regression showed that imagery ability significantly predicted reaching efficiency and that this association stayed constant across age. Findings provide the first empirical evidence that more efficient online control through development is predicted, partly, by improved action representation.

Reduced motor imagery efficiency is associated with online control difficulties in children with probable developmental coordination disorder

Recent evidence indicates that the ability to correct reaching movements in response to unexpected target changes (i.e., online control) is reduced in children with developmental coordination disorder (DCD). Recent computational modeling of human reaching suggests that these inefficiencies may result from difficulties generating and/or monitoring internal representations of movement. This study was the first to test this putative relationship empirically. We did so by investigating the degree to which the capacity to correct reaching mid-flight could be predicted by motor imagery (MI) proficiency in a sample of children with probable DCD (pDCD). Thirty-four children aged 8 to 12 years (17 children with pDCD and 17 age-matched controls) completed the hand rotation task, a well-validated measure of MI, and a double-step reaching task (DSRT), a protocol commonly adopted to infer one's capacity for correcting reaching online. As per previous research, children with pDCD demonstrated inefficiencies in their ability to generate internal action representations and correct their reaching online, demonstrated by inefficient hand rotation performance and slower correction to the reach trajectory following unexpected target perturbation during the DSRT compared to age-matched controls. Critically, hierarchical moderating regression demonstrated that even after general reaching ability was controlled for, MI efficiency was a significant predictor of reaching correction efficiency, a relationship that was constant across groups. Ours is the first study to provide direct pilot evidence in support of the view that a decreased capacity for online control of reaching typical of DCD may be associated with inefficiencies generating and/or using internal representations of action.