The effects of noise exposure on nitric oxide synthase knockout mice

This paper studies the role of nitric oxide (NOS 1, NOS 2, and NOS 3 genes) in the mouse cochlea and in noise-induced hearing loss (NIHL). Mice genetically deficient of the NOS 2 and NOS 3 genes were protected from NIHL, indicating that one or both of these genes may be responsible for producing nitric oxide that damages the inner ear when exposed to harmful levels of noise.

Injection of adult mouse mesenchymal stem cells into the developing chick inner ear

This series of experiments attempted to characterize the abilities of stem cells derived from bone marrow and adipose tissue to integrate into the sensory epithelium of the inner ear and to differentiate into hair cells or neural cell types.

Eighth nerve degeneration in the deafness mouse

This paper discusses a study done to examine regeneration of spiral ganglion cells in the deafness mouse.

Anatomic correlates of strial presbycusis in recombinant inbred mouse strains

This project attempts to identify anatomic features that predict the range of the ‘normal’ endocochlear potential in young inbred mice. Cochlear lateral wall histologic metrics were compared in recombinant inbred (RI) mouse strains formed from BALB/c and C57BL/6 mice.