1 resultado para 3 ` non-coding region
em Doria (National Library of Finland DSpace Services) - National Library of Finland, Finland
Filtro por publicador
- Aberdeen University (1)
- Aberystwyth University Repository - Reino Unido (2)
- Academic Archive On-line (Jönköping University; Sweden) (1)
- AMS Tesi di Dottorato - Alm@DL - Università di Bologna (19)
- AMS Tesi di Laurea - Alm@DL - Università di Bologna (2)
- Aquatic Commons (5)
- ArchiMeD - Elektronische Publikationen der Universität Mainz - Alemanha (11)
- Archive of European Integration (1)
- Archivo Digital para la Docencia y la Investigación - Repositorio Institucional de la Universidad del País Vasco (2)
- Aston University Research Archive (3)
- B-Digital - Universidade Fernando Pessoa - Portugal (1)
- Biblioteca de Teses e Dissertações da USP (3)
- Biblioteca Digital da Produção Intelectual da Universidade de São Paulo (27)
- Biblioteca Digital da Produção Intelectual da Universidade de São Paulo (BDPI/USP) (15)
- Biblioteca Digital de Teses e Dissertações Eletrônicas da UERJ (4)
- Bioline International (3)
- BORIS: Bern Open Repository and Information System - Berna - Suiça (53)
- Boston University Digital Common (1)
- Brock University, Canada (10)
- Bucknell University Digital Commons - Pensilvania - USA (1)
- CaltechTHESIS (4)
- Cambridge University Engineering Department Publications Database (6)
- CentAUR: Central Archive University of Reading - UK (18)
- Chinese Academy of Sciences Institutional Repositories Grid Portal (57)
- Cochin University of Science & Technology (CUSAT), India (3)
- Coffee Science - Universidade Federal de Lavras (1)
- CORA - Cork Open Research Archive - University College Cork - Ireland (4)
- Deakin Research Online - Australia (29)
- DI-fusion - The institutional repository of Université Libre de Bruxelles (2)
- Digital Archives@Colby (1)
- Digital Commons - Michigan Tech (2)
- Digital Commons at Florida International University (5)
- Digital Repository at Iowa State University (1)
- DigitalCommons@The Texas Medical Center (21)
- Doria (National Library of Finland DSpace Services) - National Library of Finland, Finland (1)
- Duke University (17)
- eResearch Archive - Queensland Department of Agriculture; Fisheries and Forestry (7)
- FUNDAJ - Fundação Joaquim Nabuco (2)
- Gallica, Bibliotheque Numerique - Bibliothèque nationale de France (French National Library) (BnF), France (10)
- Glasgow Theses Service (7)
- Helda - Digital Repository of University of Helsinki (14)
- Illinois Digital Environment for Access to Learning and Scholarship Repository (1)
- Indian Institute of Science - Bangalore - Índia (57)
- Instituto Gulbenkian de Ciência (1)
- Instituto Nacional de Saúde de Portugal (1)
- Instituto Politécnico do Porto, Portugal (2)
- Lume - Repositório Digital da Universidade Federal do Rio Grande do Sul (1)
- Massachusetts Institute of Technology (1)
- National Center for Biotechnology Information - NCBI (84)
- Plymouth Marine Science Electronic Archive (PlyMSEA) (3)
- Publishing Network for Geoscientific & Environmental Data (6)
- QSpace: Queen's University - Canada (1)
- QUB Research Portal - Research Directory and Institutional Repository for Queen's University Belfast (63)
- Queensland University of Technology - ePrints Archive (95)
- RCAAP - Repositório Científico de Acesso Aberto de Portugal (1)
- Repositório Científico do Instituto Politécnico de Lisboa - Portugal (1)
- Repositório do Centro Hospitalar de Lisboa Central, EPE - Centro Hospitalar de Lisboa Central, EPE, Portugal (2)
- Repositório Institucional da Universidade de Aveiro - Portugal (2)
- Repositório Institucional da Universidade Estadual de São Paulo - UNESP (1)
- Repositório Institucional UNESP - Universidade Estadual Paulista "Julio de Mesquita Filho" (95)
- RUN (Repositório da Universidade Nova de Lisboa) - FCT (Faculdade de Cienecias e Technologia), Universidade Nova de Lisboa (UNL), Portugal (3)
- SAPIENTIA - Universidade do Algarve - Portugal (1)
- Savoirs UdeS : plateforme de diffusion de la production intellectuelle de l’Université de Sherbrooke - Canada (1)
- Universidad de Alicante (1)
- Universidad del Rosario, Colombia (4)
- Universidad Politécnica de Madrid (4)
- Universidade Complutense de Madrid (1)
- Universidade de Lisboa - Repositório Aberto (4)
- Universidade Federal do Pará (5)
- Universidade Federal do Rio Grande do Norte (UFRN) (6)
- Universita di Parma (2)
- Universitat de Girona, Spain (3)
- Université de Lausanne, Switzerland (12)
- Université de Montréal (2)
- Université de Montréal, Canada (22)
- Université Laval Mémoires et thèses électroniques (1)
- University of Michigan (3)
- University of Queensland eSpace - Australia (32)
- University of Washington (1)
- WestminsterResearch - UK (2)
Resumo:
Carbonic anhydrases are enzymes that are ubiquitously found in all organisms that are engaged in catalyzing the hydration of carbon dioxide to form bicarbonate and proton and vice versa. They are crucial in the process of respiration, bone resorption, pH regulation, ion transport, and photosynthesis in plants. Out of the five classes of carbonic anhydrase α, β, γ, δ, ζ this study focused in the α carbonic anhydrases. This class of CAs constitute of 16 subfamilies in mammals that include 3 non-active enzymes known as Carbonic Anhydrase Related Proteins. The inactiveness of these enzymes is due to the loss of one or more Histidine residues in the active site. This thesis was conducted based on the aim of studying evolutionary analysis of carbonic anhydrase sequences from organisms spanning from the Cambrian age. It was carried out in two phases. The first phase was the sequence collection, which involved many biological sequence databases as a source. The scope of this segment included sequence alignments and analysis of the sequence manually and in an automated form incorporating few analysis tools. The second Phase was phylogenetic analysis and exploring the subcellular location of the proteins, which was key for the evolutionary analysis. Through the medium of the methods conducted with respect to the phases mentioned above, it was possible to accomplish the desired result. Certain thought-provoking sequences were come across and analyzed thoroughly. Whereas, Phylogenetics showed interesting results to bolster previous findings and new findings as well which lay bedrock for future intensified studies.