2 resultados para star polymers

em WestminsterResearch - UK


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On the whole, a man who is elected as Pope is well on in years. Some, despite this, have managed to reign for a long time, Leo XIII for instance who came to the throne when he was already seventy in 1878, reigned for twenty five years. Wojtyla was elected when he was only fifty eight, in 1978. In the last century or so, the papacy has become visible worldwide through the mass media. On his accession, Wojtyla was presented as a man's man, a sportsman - according to Professor Eamon Duffy of Cambridge University - as a Bishop with balls. Like other media stars who have stayed the test of time, e.g. Madonna, David Bowie, it seems that he has been able to reinvent his media image to some extent; from the active sportsman to the benevolent grandfather to the ailing figure we see today. He has taken on the aspect of a media star, a world traveller, a spiritual leader, a politician, a mediator and a peace leader. He has been described as the most-photographed person on the planet. This paper will attempt to trace these changes and to ascertain, using Vatican and media sources to discover how much of this continual change is driven by the personality of John Paul himself and how much is a deliberate policy on the part of the Vatican.

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AIMS: The aim of this study was to evaluate the impact of the administration of microencapsulated Lactobacillus plantarum CRL 1815 with two combinations of microbially derived polysaccharides, xanthan : gellan gum (1%:0·75%) and jamilan : gellan gum (1%:1%), on the rat faecal microbiota. METHODS AND RESULTS: A 10-day feeding study was performed for each polymer combination in groups of 16 rats fed either with placebo capsules, free or encapsulated Lact. plantarum or water. The composition of the faecal microbiota was analysed by fluorescence in situ hybridization and temporal temperature gradient gel electrophoresis. Degradation of placebo capsules was detected, with increased levels of polysaccharide-degrading bacteria. Xanthan : gellan gum capsules were shown to reduce the Bifidobacterium population and increase the Clostridium histolyticum group levels, but not jamilan : gellan gum capsules. Only after administration of jamilan : gellan gum-probiotic capsules was detected a significant increase in Lactobacillus-Enterococcus group levels compared to controls (capsules and probiotic) as well as two bands were identified as Lact. plantarum in two profiles of ileum samples. CONCLUSIONS: Exopolysaccharides constitute an interesting approach for colon-targeted delivery of probiotics, where jamilan : gellan gum capsules present better biocompatibility and promising results as a probiotic carrier. SIGNIFICANCE AND IMPACT OF STUDY: This study introduces and highlights the importance of biological compatibility in the encapsulating material election, as they can modulate the gut microbiota by themselves, and the use of bacterial exopolysaccharides as a powerful source of new targeted-delivery coating material.