1 resultado para Gut microbiota
em Worcester Research and Publications - Worcester Research and Publications - UK
Filtro por publicador
- ABACUS. Repositorio de Producción Científica - Universidad Europea (1)
- Aberdeen University (8)
- Abertay Research Collections - Abertay University’s repository (1)
- Acceda, el repositorio institucional de la Universidad de Las Palmas de Gran Canaria. España (2)
- AMS Tesi di Dottorato - Alm@DL - Università di Bologna (18)
- AMS Tesi di Laurea - Alm@DL - Università di Bologna (2)
- Aquatic Commons (6)
- ArchiMeD - Elektronische Publikationen der Universität Mainz - Alemanha (2)
- Archimer: Archive de l'Institut francais de recherche pour l'exploitation de la mer (3)
- Aston University Research Archive (3)
- Biblioteca de Teses e Dissertações da USP (3)
- Biblioteca Digital da Produção Intelectual da Universidade de São Paulo (4)
- Biblioteca Digital da Produção Intelectual da Universidade de São Paulo (BDPI/USP) (3)
- Biblioteca Digital de Teses e Dissertações Eletrônicas da UERJ (2)
- Bioline International (2)
- BORIS: Bern Open Repository and Information System - Berna - Suiça (119)
- CaltechTHESIS (2)
- Cambridge University Engineering Department Publications Database (4)
- CentAUR: Central Archive University of Reading - UK (262)
- Chinese Academy of Sciences Institutional Repositories Grid Portal (9)
- Cochin University of Science & Technology (CUSAT), India (2)
- CORA - Cork Open Research Archive - University College Cork - Ireland (39)
- Deakin Research Online - Australia (40)
- DI-fusion - The institutional repository of Université Libre de Bruxelles (1)
- Digital Commons at Florida International University (1)
- Digital Peer Publishing (1)
- DigitalCommons - The University of Maine Research (3)
- DigitalCommons@The Texas Medical Center (3)
- Digitale Sammlungen - Goethe-Universität Frankfurt am Main (26)
- Doria (National Library of Finland DSpace Services) - National Library of Finland, Finland (3)
- eResearch Archive - Queensland Department of Agriculture; Fisheries and Forestry (1)
- Fachlicher Dokumentenserver Paedagogik/Erziehungswissenschaften (1)
- FUNDAJ - Fundação Joaquim Nabuco (1)
- Gallica, Bibliotheque Numerique - Bibliothèque nationale de France (French National Library) (BnF), France (1)
- Glasgow Theses Service (1)
- Helda - Digital Repository of University of Helsinki (9)
- Indian Institute of Science - Bangalore - Índia (6)
- Instituto Gulbenkian de Ciência (2)
- Instituto Politécnico do Porto, Portugal (1)
- Lume - Repositório Digital da Universidade Federal do Rio Grande do Sul (1)
- National Center for Biotechnology Information - NCBI (9)
- Plymouth Marine Science Electronic Archive (PlyMSEA) (12)
- Publishing Network for Geoscientific & Environmental Data (49)
- QUB Research Portal - Research Directory and Institutional Repository for Queen's University Belfast (38)
- Queensland University of Technology - ePrints Archive (21)
- RDBU - Repositório Digital da Biblioteca da Unisinos (1)
- Repositorio Academico Digital UANL (1)
- Repositório Alice (Acesso Livre à Informação Científica da Embrapa / Repository Open Access to Scientific Information from Embrapa) (5)
- Repositório Científico da Universidade de Évora - Portugal (1)
- Repositório Científico do Instituto Politécnico de Lisboa - Portugal (1)
- Repositório Institucional UNESP - Universidade Estadual Paulista "Julio de Mesquita Filho" (127)
- RUN (Repositório da Universidade Nova de Lisboa) - FCT (Faculdade de Cienecias e Technologia), Universidade Nova de Lisboa (UNL), Portugal (2)
- SAPIENTIA - Universidade do Algarve - Portugal (1)
- Savoirs UdeS : plateforme de diffusion de la production intellectuelle de l’Université de Sherbrooke - Canada (1)
- School of Medicine, Washington University, United States (1)
- Scielo España (1)
- Universidad de Alicante (1)
- Universidad del Rosario, Colombia (2)
- Universidad Politécnica de Madrid (8)
- Universidade Complutense de Madrid (2)
- Universidade Federal do Rio Grande do Norte (UFRN) (2)
- Universitat de Girona, Spain (3)
- Universitätsbibliothek Kassel, Universität Kassel, Germany (2)
- Université de Lausanne, Switzerland (3)
- Université de Montréal, Canada (3)
- University of Connecticut - USA (1)
- University of Michigan (13)
- University of Queensland eSpace - Australia (7)
- University of Washington (2)
- WestminsterResearch - UK (10)
- Worcester Research and Publications - Worcester Research and Publications - UK (1)
Resumo:
Diabetes is a condition of multifactorial origin, involving several molecular mechanisms related to the intestinal microbiota for its development. In type 2 diabetes, receptor activation and recognition by microorganisms from the intestinal lumen may trigger inflammatory responses, inducing the phosphorylation of serine residues in insulin receptor substrate-1, reducing insulin sensitivity. In type 1 diabetes, the lowered expression of adhesion proteins within the intestinal epithelium favours a greater immune response that may result in destruction of pancreatic β cells by CD8+ T-lymphocytes, and increased expression of interleukin-17, related to autoimmunity. Research in animal models and humans has hypothesized whether the administration of probiotics may improve the prognosis of diabetes through modulation of gut microbiota. We have shown in this review that a large body of evidence suggests probiotics reduce the inflammatory response and oxidative stress, as well as increase the expression of adhesion proteins within the intestinal epithelium, reducing intestinal permeability. Such effects increase insulin sensitivity and reduce autoimmune response. However, further investigations are required to clarify whether the administration of probiotics can be efficiently used for the prevention and management of diabetes.