1 resultado para Antibiotics, Misuse, Overuse, Intervention Strategies, Children, Upper Respiratory Tract Infections, Saudi Arabia
em DI-fusion - The institutional repository of Université Libre de Bruxelles
Filtro por publicador
- Abertay Research Collections - Abertay University’s repository (1)
- Acceda, el repositorio institucional de la Universidad de Las Palmas de Gran Canaria. España (1)
- AMS Tesi di Dottorato - Alm@DL - Università di Bologna (4)
- ArchiMeD - Elektronische Publikationen der Universität Mainz - Alemanha (2)
- Archive of European Integration (1)
- Archivo Digital para la Docencia y la Investigación - Repositorio Institucional de la Universidad del País Vasco (2)
- Aston University Research Archive (8)
- B-Digital - Universidade Fernando Pessoa - Portugal (6)
- Biblioteca de Teses e Dissertações da USP (2)
- Biblioteca Digital | Sistema Integrado de Documentación | UNCuyo - UNCUYO. UNIVERSIDAD NACIONAL DE CUYO. (3)
- Biblioteca Digital da Produção Intelectual da Universidade de São Paulo (33)
- Biblioteca Digital da Produção Intelectual da Universidade de São Paulo (BDPI/USP) (8)
- Biblioteca Digital de Teses e Dissertações Eletrônicas da UERJ (4)
- Bioline International (5)
- BORIS: Bern Open Repository and Information System - Berna - Suiça (111)
- Brock University, Canada (7)
- Bucknell University Digital Commons - Pensilvania - USA (1)
- Cambridge University Engineering Department Publications Database (1)
- CentAUR: Central Archive University of Reading - UK (19)
- Chinese Academy of Sciences Institutional Repositories Grid Portal (2)
- Comissão Econômica para a América Latina e o Caribe (CEPAL) (2)
- CORA - Cork Open Research Archive - University College Cork - Ireland (2)
- Cornell: DigitalCommons@ILR (1)
- Deakin Research Online - Australia (93)
- DI-fusion - The institutional repository of Université Libre de Bruxelles (1)
- Digital Commons @ DU | University of Denver Research (1)
- Digital Commons at Florida International University (9)
- DigitalCommons@The Texas Medical Center (24)
- DigitalCommons@University of Nebraska - Lincoln (1)
- DRUM (Digital Repository at the University of Maryland) (2)
- Duke University (8)
- eResearch Archive - Queensland Department of Agriculture; Fisheries and Forestry (8)
- Escola Superior de Educação de Paula Frassinetti (3)
- Greenwich Academic Literature Archive - UK (1)
- Helda - Digital Repository of University of Helsinki (13)
- Indian Institute of Science - Bangalore - Índia (4)
- Institutional Repository of Leibniz University Hannover (1)
- Instituto Nacional de Saúde de Portugal (3)
- Instituto Politécnico de Santarém (2)
- Instituto Politécnico de Viseu (5)
- Instituto Politécnico do Porto, Portugal (5)
- Lume - Repositório Digital da Universidade Federal do Rio Grande do Sul (7)
- Memoria Académica - FaHCE, UNLP - Argentina (24)
- Ministerio de Cultura, Spain (1)
- National Center for Biotechnology Information - NCBI (15)
- Portal de Revistas Científicas Complutenses - Espanha (1)
- QSpace: Queen's University - Canada (1)
- QUB Research Portal - Research Directory and Institutional Repository for Queen's University Belfast (70)
- Queensland University of Technology - ePrints Archive (124)
- RCAAP - Repositório Científico de Acesso Aberto de Portugal (1)
- ReCiL - Repositório Científico Lusófona - Grupo Lusófona, Portugal (1)
- REPOSITÓRIO ABERTO do Instituto Superior Miguel Torga - Portugal (2)
- Repositorio Académico de la Universidad Nacional de Costa Rica (1)
- Repositório Científico da Universidade de Évora - Portugal (3)
- Repositório Científico do Instituto Politécnico de Lisboa - Portugal (6)
- Repositório Científico do Instituto Politécnico de Santarém - Portugal (2)
- Repositorio de la Universidad de Cuenca (1)
- Repositório digital da Fundação Getúlio Vargas - FGV (2)
- Repositório do Centro Hospitalar de Lisboa Central, EPE - Centro Hospitalar de Lisboa Central, EPE, Portugal (1)
- Repositório Institucional da Universidade de Aveiro - Portugal (8)
- Repositório Institucional UNESP - Universidade Estadual Paulista "Julio de Mesquita Filho" (75)
- Research Open Access Repository of the University of East London. (1)
- RUN (Repositório da Universidade Nova de Lisboa) - FCT (Faculdade de Cienecias e Technologia), Universidade Nova de Lisboa (UNL), Portugal (1)
- Savoirs UdeS : plateforme de diffusion de la production intellectuelle de l’Université de Sherbrooke - Canada (2)
- School of Medicine, Washington University, United States (1)
- Scielo España (1)
- Universidad de Alicante (2)
- Universidad del Rosario, Colombia (32)
- Universidad Politécnica de Madrid (5)
- Universidade de Lisboa - Repositório Aberto (3)
- Universidade dos Açores - Portugal (1)
- Universidade Federal de Uberlândia (1)
- Universidade Federal do Pará (6)
- Universidade Federal do Rio Grande do Norte (UFRN) (12)
- Universidade Metodista de São Paulo (6)
- Universidade Técnica de Lisboa (1)
- Universita di Parma (1)
- Universitat de Girona, Spain (2)
- Université de Lausanne, Switzerland (8)
- Université de Montréal (1)
- Université de Montréal, Canada (24)
- University of Canberra Research Repository - Australia (1)
- University of Connecticut - USA (1)
- University of Michigan (6)
- University of Queensland eSpace - Australia (29)
- University of Washington (7)
Resumo:
Specific anti-polysaccharide antibody deficiency (SPAD) is an immune disorder. Diagnostic criteria have not yet been defined clearly. One hundred and seventy-six children evaluated for recurrent respiratory tract infections were analysed retrospectively. For each subject, specific anti-pneumococcal antibodies had been measured with two enzyme-linked immunosorbent assays (ELISAs), one overall assay (OA) using the 23-valent pneumococcal polysaccharide vaccine (23-PPSV) as detecting antigen and the other purified pneumococcal polysaccharide serotypes (serotype-specific assay, SSA) (serotypes 14, 19F and 23F). Antibody levels were measured before (n = 176) and after (n = 93) immunization with the 23-PPSV. Before immunization, low titres were found for 138 of 176 patients (78%) with OA, compared to 20 of 176 patients (11%) with the SSA. We found a significant correlation between OA and SSA results. After immunization, 88% (71 of 81) of the patients considered as responders in the OA test were also responders in the SSA; 93% (71 of 76) of the patients classified as responders according to the SSA were also responders in the OA. SPAD was diagnosed in 8% (seven of 93) of patients on the basis of the absence of response in both tests. Thus, we propose to use OA as a screening test for SPAD before 23-PPSV immunization. After immunization, SSA should be used only in case of a low response in OA. Only the absence of or a very low antibody response detected by both tests should be used as a diagnostic criterion for SPAD.