202 resultados para DNA Teses
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To test the hypothesis that mitochondrial DNA (mtDNA) variants contribute to the susceptibility to schizophrenia, we sequenced the entire mtDNAs from 93 Japanese schizophrenic patients. Three non-synonymous homoplasmic variants in subunit six of the ATP s
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DNADNA,TypeBTypeA,,TypeATypeB,TypeATypeB,TypeBTypeA,,TypeBTypeA;TypeBTypeATypeA,TypeATypeATypeA,TypeB,DNA,
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60 , Kimura : DNA , DNA , DNA : Tajima (1989) D , , , DNA , ,
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,413DNA(mtDNA),Apa,Ava,BamH,Bcl,BcIBgl,Cla,Dra, EcoR,EcoR,Hae,Hind,Kpn,Pst,Pvu,Sac,Sal,Sma,StuXho20DNA 15.8KbDra7Ava6EcoRStu5HindHae4 BamH,Bgl,PstPvu3ApaCla14
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, DNA .
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STM DNA , . , ,
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, 5-. , 5-, DNA . DNA. , 5-. 5-, (Cm~(5)CT). DNA, GCAT
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DNA (mtDNA), . mtDNA . mtDNA , . , : 1), 2), 3)DNase, 4). , ,
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16150mtDNA(RFLP)31, Hae -13EcoRV-3Pst-3 , 28mtDNAUPGmtDNA: mtDNA; , 4428
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The three-dimensional molecular models of DNA triple helices and triple-stranded brain-like structure were built up by molecular architecture, and their structural features and energy decomposition were examined. The results showed: (i) The base triplet is the element forming braid-like and triple helix DNA; (ii) Under specified conditions, DNA could form the triplet-stranded braid-like structure; (iii) DNA stability of the braid-like structure is less than that of the triple helix structure. (C) 1995 Academic Press Limited.
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5-methylcytosine (m(5)C) as a rare base exists in eukaryotic genomes, which is a normal constitution in many eukaryotic DNA and the existence of m(5)C is a feature of eukaryotic DNA. Under regular physiological conditions, cytosine of eukaryotic DNA is usually methylated. Up to the present, many people consider that the m(5)C may be mutation hotspots by the deamination leading to gene mutation. Our study indicated that the spontaneous mutation caused by the transition of G.C --> A.T, in eukaryotic DNA, may result from the tautomer changing of base pairs and may also be cause by other factor actions, however it could not be caused by the deamination of m(5)C.
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18DNA(mtDNA),Apa IAva IBamH IBcl IBgl IBgl IICla IDra IEcoR IEcoR VHae IHind IIIKpn IPst IPvu IISac ISal ISma IStu IXba I20 DNA15.8Kb;:Dra I7,Ava II6,EcoR VStu I5,Hind IIIHea II4,BamH IBgl IIPst IPvu II3,Apa ICla I2,1
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DNA, DNA100bp1kbDNAbPCRDNA307bp b(364bp)28 , 4(DraxbaHaeHpa), HaeHap 310
